3D IMAGES OF MITOCHONDRIA
(C.A. Mannella, Wadsworth Center)
Mitochondria are the cellular organelles that generate ATP1
from oxidation of carbohydrates and other "food" molecules.
Shown here are 3D reconstructions of rat-liver mitochondria obtained by
high-voltage (1000 kV) electron tomography at the
Wadsworth Center's Biological Microscopy and Image Reconstruction Resource
This is a cluster of 14 mitochondria (yellow) in the vicinity of a
multilayered stack of endoplasmic reticulum (blue-green). The close proximity
between mitochondrial and ER membranes may be important for regulation
of cellular Ca++ levels.
||This is a look inside an isolated mitochondrion, showing the outer
membrane (OM), inner peripheral membrane (IM), and some of the internal
compartments called cristae (C) formed by infolding of the inner membrane.
Arrows point to narrow tubular regions of the IM that connect cristae to
periphery and to each other. For a 3D Gallery model, click here.
Both figures are from Mannella (2000) Journal of Bioenergetics and Biomembranes,
Vol. 32, in press.
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