Overview
The Department of Biomedical Sciences at the Wadsworth Center
offers M.S. and Ph.D. programs in Molecular Genetics (MG). This
program brings together scientists studying the structure and
function of genes and the roles they play in fundamental biological
processes and human genetic diseases. Faculty within the Molecular
Genetics Program investigate the molecular biology and genetics
of humans as well as mice, Drosophila, yeast, archaea, bacteria
and phage. Areas of scientific interest include development, cell
cycle, mobile genetic elements, recombination, RNA splicing, transcription,
and viral replication. For more information on the faculty of
the Molecular Genetics Department, go to the MG
faculty page.
Resources
The Wadsworth Center provides a variety of state-of-the-art core
facilities. The molecular genetics core provides in-house DNA
synthesis and sequencing services as well as equipment for general
use including a scanning densitometer, luminescent spectrometer,
phosphorimager, pulsed-field, temperature-gradient and PAGE electrophoresis
chambers, and PCR machines. Other cores available to program faculty
include a microarray facility, amino acid analysis and protein
sequencing, biochemistry, biological mass spectrometry, immunology-hybridoma,
macromolecular crystallography, peptide synthesis, NMR, light
and electron microscopy, and a transgenic mouse facility. For
more information on Wadsworth Center resources, go to the resources
page.
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TBicoid homeodomain
mutations that affect cooperative DNA binding. (Burz & Hanes,
JMB 305, 219-230) ext
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