A R C H I V E D


3rd Albany Conference on

Frontiers of Mitochondrial Research
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Last update: 
Sept 11, 2000

PROGRAM

3rd Albany Conference on
Frontiers of Mitochondrial Research

September 14-17, 2000
Rensselaerville, NY 
 
 

THURSDAY EVENING - 7:30 PM

Opening Session

7:30 PM

Carmen Mannella
President, Albany Conference Foundation
Welcome and Opening Remarks

8:00 PM

Simon Melov
Buck Center for Research and Aging
A mouse model for mitochondrial oxidative stress
 

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FRIDAY MORNING

Structure/Function
(Chair:  J. Lemasters, Univ. North Carolina at Chapel Hill)

9:00 AM
Carmen Mannella
Wadsworth Center
Dynamics of mitochondrial inner membrane folding inferred from EM tomography
9:30 AM
Guy Perkins
University of California, San Diego
Dual-specific A kinase anchoring proteins target mitochondria
10:00 AM
Frank Gellerich
University of Halle, Germany
Bioenergetic importance of mitochondrial outer membrane as diffusion barrier under normal and impaired conditions
10:30 AM
BREAK
11:00 AM
Uwe Schlattner
Institute of Cell Biology, Switzerland
Mitochondrial creatine kinase:  involvement in energy channeling and control of permeability transition
11:30 AM
Martin Klingenberg
University of Munich, Germany
A fresh look at uncoupling proteins

FRIDAY AFTERNOON

2:00-4:00 PM

Workshop:  Mitochondria and Disease
(Chair:  G. Cortopassi, University of California, Davis)

Paolo Bernardi - University of Padova
Ian Reynolds - University of Pittsburgh
Yau-Huei Wei -National Yang-Ming University
Gino Cortopassi - University of California, Davis
 

FRIDAY EVENING

Permeability Transition
(Chair:  P. Bernardi, Univ. Padova)

7:15 PM
Andrew Halestrap
University of Bristol, United Kingdom
The molecular mechanism of the mitochondrial permeability transition pore
7:45 PM
Lihua He
University of North Carolina at Chapel Hill
Characterization of cyclosporin A sensitive and insensitive permeability transition pores in rat liver mitochondria
8:15 PM 
BREAK
8:30 PM
Valeria Petronilli
University of Padova, Italy
The relationship between the mitochondrial permeability transition and cell death
9:00 PM
Anna-Liisa Nieminen
Case Western Reserve University
Mitochondrial swelling, depolarization, and permeability transition during Bax-induced apoptosis in hepatocytes

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SATURDAY MORNING

Cytochrome c Release
(Chair:  A. Murphy, MitoKor)

9:00 AM
Roman Eliseev
University of Rochester Medical Center
Dysfunction of mitochondria and cytochrome c release during apoptosis
9:30 AM
Alexander Andreyev
MitoKor
 Ca2+ uptake and release of cytochrome c in neural cell mitochondria
10:00 AM
Jochen Prehn
University of Muenster, Germany
Multiple kinetics of mitochondrial cytochrome c release in apoptosis
10:30 AM
BREAK
11:00 AM
Francois Ichas
Universite Victor Segalen Bordeaux 2, France
The permeability transition pore signals apoptosis by directing Bax translocation
11:30 AM
Brian Polster
University of Maryland School of Medicine
Bax BH3 peptide induces permeability transition-independent release of cytochrome c from neural cell but not isolated brain or liver mitochondria

SATURDAY AFTERNOON

Workshop(s):  To Be Announced

2:00-4:00 PM
Workshop(s)

SATURDAY EVENING

Bcl-2 Proteins and Channels
(Chair:  M. Forte,  Oregon Health Sciences University)

7:15 PM
Atan Gross
The Weizmann Institute of Science, Israel
The role of BID in apoptosis
7:45 PM 
Bruno Antonsson
Serono Pharmaceutical Research Institute
Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells
8:15 PM 
BREAK
8:30 PM 
Marco Colombini
University of Maryland
Bcl-xL alters the gating properties of VDAC channels isolated from rat liver mitochondria
9:00 PM 
Kathleen Kinnally
New York University
Death signal leads to the formation of a novel h igh-conductance channel in the mitochondrial outer membrane

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SUNDAY MORNING

Calcium
(Chair:  I. Reynolds, University of Pittsburgh)

9:00 AM
Gyorgy Hajnoczky
Thomas Jefferson University
Mitochondrial Ca2+ signaling in life and death
9:30 AM
Jennifer Buckman
University of Pittsburgh
Dynamics of mitochondrial membrane potential in neurons and astrocytes
10:00 AM
BREAK
10:15 AM
David Nicholls
Buck Institute
Mitochondrial membrane potential in cultured neural cells:  distinctive responses to apoptotic stimuli, NMDA and AMPA receptor activation and modelling with a 'virtual cell'
10:45 AM
Shey-Shing Sheu
University of Rochester Medical School
Visualization and modification of the mitochondrial peremability transition pore in striatal neurons
 
11:15 AM
Closing Discussion


For further information contact...Carmen Mannella: carmen@wadsworth.org

 

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