New York State Department of Health - Wadsworth Center - Cytohematology Proficiency Testing

Slide 039 [100X]

This slide was taken from the peripheral blood of a 55 year-old female that was asymptomatic. Her CBC showed mild anemia and thrombocytosis with a platelet count of 1550 X 10³/µL. Her differential showed 15% blasts, 3% myelocytes and 12% metamyelocytes. On physical examination, she was found to have an enlarged spleen. Her bone marrow aspirate could not be evaluated for technical reasons, however, the bone marrow biopsy was cellular with fibrosis. Megakaryocytes were markedly increased and included atypical forms. Myeloid and erythroid cells were present and both lines exhibited maturation. Special stains showed marked increase in reticulin. These features are consistent with a myeloproliferative disorder. The red blood cell indicated by the arrow demonstrates basophilic stippling.

NUMBER OF RESPONSES	CELL CODE AND TYPE
495	code 20- basophilic stippling

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