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New York State Department of Health - Wadsworth Center - Cytohematology Proficiency Testing

Slide 153 [100X]        Click here for a higher resolution image.

The correct response for the arrowed cell is Pelger-Huët (Code 22). This slide was taken from a case of a patient diagnosed with Pelger-Huët anomaly. Both of the cells seen on this slide are bi-lobed, the nucleus has failed to properly segment. While by definition they are segmented neutrophils, when the majority (or in this instance two cells in one field) appear bi-lobed, a diagnosis of Pelger-Huët anomaly is appropriate. The neutrophils of this benign anomaly appear to function normally.

Number of Responses

Percent of Laboratories

Cell Code and Type

415

97.0%

Code 22:  Pelger-Huët

10

2.3%

Code 09:  Segmented neutrophil

2

0.5%

Code 20: Seg /band neutrophil with toxic granulation 

1

0.2%

Code 13:  Eosinophil

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