Slide 002
Slide 002:

Diagnosis: Chronic lymphocytic leukemia (CLL). According to

Barbara Brown,

Hematology: Principles and Procedures, Sixth Edition:

 "The peripheral blood smear in patients with chronic lymphocytic leukemia (CLL) shows 60-95% lymphocytes. These cells are generally the small type of mature lymphocyte that often show a small

cleft or indentation

in the condensed chromatin of the nucleus. Lymphoblasts are generally absent from the peripheral blood, but a rare prolymphocyte may sometimes be found. These lymphocytes are somewhat more fragile than normal, resulting in many of the cells being ruptured during the preparation of the blood smear. Therefore, large numbers of

smudge cells

are usually seen on the Wright stained smear."

Available data:

68 year- old female.

Four hundred sixty-three (463) laboratories passed this slide with a score of 80% or higher. Ten (10) laboratories received scores below 80%.

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Laboratory Data

WBC

10.2 x 10

9

/ L

RBC

5.00 X1012/L

Hemoglobin

14.8 g/dL

Hematocrit

45.9 %

MCV

91.8fL

MCH

29.5pg

MCHC

32.2g/dL

Platelet

171 X 109 /L