Döhle bodies

These four images were taken from the 1997 Cytohematology Proficiency Test Event - Slide 003. Döhle bodies appear as single or multiple light blue or gray staining areas in the cytoplasm of a neutrophil. They are rough endoplasmic reticulum containing ribonucleic acid (RNA) and may represent localized failure of the cytoplasm to mature. Döhle bodies are found in infections, poisoning, burns, and following chemotherapy. Back to Slide 003