Smart Lighting Center – Bio-Imaging Team

Research Focus and Benefits

Smart lighting in bio-imaging

• Replacement of transmitted & reflected light sources.
  Improved Color balance
  higher S/N
  lower dose
• Spectral control of lighting and detector in fluorescence microscopes.
  Improved detection of absorbent stains
  higher S/N

Scanning microscopy with integrated LED lighting

• Integrated adaptive lighting in scanning optical microscope for tracking multiple spectral, spatial, and temporal events.
  Improved resolution for large field
  dynamic live organism observation
• Extension to subsurface (OCT) & phase contrast imaging.
  Improved resolution
  depth penetration
  contrast in large field of view

Spectral control

• Spectrum optimization (multi-chip LED module).
  Increase temporal resolution
  lower dose
  higher S/N
  more fluorochromes
• Spectrum control through color temperature feedback .
  Higher sensitivity
  greater color discrimination
  automation