Mycobacteriology Laboratory
Selected Publications
2010
Halse T. A., Edwards J., Cunningham P. L., Wolfgang W. J., Dumas N. B., Escuyer V. and Musser, K. A. Combined Real-Time PCR and rpoB gene pyrosequencing for the rapid identification of Mycobacterium tuberculosis and the determination of rifampin resistance directly on clinical specimens. J. Clin. Microbiol. Apr 2010; 48: 1182 - 1188 (2010)
2008
Akos Somoskovi, Jillian Dormandy, Jeremy Rivenburg, Maria Pedrosa, Melinda McBride, and Max Salfinger Direct comparison of the Genotype MTBC and genomic deletion assays in terms of their ability to distinguish between members of the Mycobacterium tuberculosis complex in clinical isolates and in clinical specimens J. Clin. Microbiol, May 2008, p. 1854–1857 Vol. 46, No. 5
2006
Akos Somoskovi, Jillian Dormandy, Dimitra Mitsani, Jeremy Rivenburg, and Max Salfinger Use of Smear-Positive Samples To Assess the PCR-Based Genotype MTBDR Assay for Rapid, Direct Detection of the Mycobacterium tuberculosis Complex as Well as Its Resistance to Isoniazid and Rifampin J. Clin. Microbiol. 44: 4459-4463. (2006)
2005
Viveiros M, Leandro C, Rodrigues L, Almeida J, Bettencourt R, Couto I, Carrilho L, Diogo J, Fonseca A, Lito L, Lopes J, Pacheco T, Pessanha M, Quirim J, Sancho L, Salfinger M, Amaral L: Direct application of the INNO-LiPA Rif.TB Line-Probe assay for the rapid identification of Mycobacterium tuberculosis complex strains and detection of rifampin resistance in 360 smear positive respiratory specimens from an area of high incidence of multidrug-resistant tuberculosis. J. Clin. Microbiol. 43:4880-4884(2005)
American Thoracic Society / Centers for Disease Control and Prevention / Infectious Disease Society of America [Nolan CH, Blumberg HM, Taylor Z, Bernardo J, Brennan PJ, Dunlap NE, Daley CL, El-Sadr WM, Etkind S, FitzGerald M , McAuley JB, Moore M, Qualls NL, Reves RR, Royce SE, Salfinger M, Starke JR, Walton W, Weis S, Young J]: Controlling tuberculosis in the Unites States Am. J. Respir. Crit. Care Med. 172:1169-1227(2005)
Winters A, Driver C, Macaraig M, Clark C, Munsiff SS, Pichardo C, Driscoll J, Salfinger M, Kreiswirth B, Jereb J, LoBue P, Lynch M:Human Tuberculosis caused by Mycobacterium bovis- New York City, 2001-2004 Morbididty Mortality Weekly Report 54:605-608 (2005)
Van Rie A, Zhemkov V, Granskaya J, Steklova L, Shpakovskaya L, Wendelboe AM, Kozlov A, Ryder R, Salfinger M: TB-HIV in St. Petersburg, Russia: A looming catastrophe? Int. J. Tuberc. Lung Dis. 9: 740-745 (2005)
Parsons LM, Salfinger M, Clobridge A, Dormandy Jillian, Mirabello L, Polletta VL, Sanic A, Sinyavskiy O, Larsen S, Driscoll J, Zickas G, Taber HW: Phenotypic and molecular characterization of isolates of Mycobacterium tuberculosis resistant to both isoniazid and ethambutol. Antimicrob Agents Chemother: 49: 2218-2225 (2005)
Flores A, Parsons LM, Pavelka M: Characterization of Novel Mycobacterium tuberculosis and Mycobacterium smegmatis Mutants Hypersusceptible to Beta-Lactam Antibiotics. J. Bact. 187: 1892-1900 (2005)
Driscoll J, Parsons LM, Salfinger M, Taber HW: Genomic analysis of the Mycobacterium tuberculosis complex: Applications to laboratory diagnosis and genotyping. Rev Med Microbiol: 16:49-58 (2005)
Espinal MA, Salfinger M: Global Impact of Multidrug Resistance. In Cole ST, KD Eisenach, D McMurray, and Jacobs Jr WR (eds). Tuberculosis and the Tubercle Bacillus, ASM Press, Washington, DC. p 101-114 (2005)
2004
Brudney K, Guttierez MC, Vincent V, Parsons LM, Salfinger M, Rastogi N, Sola C: Mycobacterium africanum genotyping using novel spacer oligonucleotides in the direct repeat locus. J. Clin. Microbiol. 42:5053-5057 (2004)
Gumbo T, Louie A, Deziel MR, Parsons LM, Salfinger M, Drusano GL: Selection of a moxifloxacin dose that suppresses Mycobacterium tuberculosis resistance using in vitro pharmacodynamic infection model and mathematical modeling. J. Infect. Dis. 190:1642-1651 (2004)
Parsons LM, Somoskovi A, Urbanczik R, Salfinger M: Laboratory diagnostic aspects of drug resistant tuberculosis. Frontiers in Bioscience 9:2086-2105 (2004)
Ashkin D, Hale Y, Hollender E, Lauzardo M, Narita M, Pitchenik AE, Salfinger M, Stambaugh JJ: Mycobacterial disease in patients with HIV infection. In Wormser GP (ed). AIDS and other manifestations of HIV infection, Elsevier (USA) p 423-478 (2004)
2003
Somoskovi A, Song Q, Mester J, Tanner C, Parsons LM, Hale YM, Salfinger M: Use of molecular methods to identify the Mycobacterium tuberculosis complex and other mycobacterial species, and to detect rifampin resistance in TB following growth detection in the BACTEC MGIT 960 system. J. Clin. Microbiol. 41:2822-2826 (2003)
Stop TB Working Group on DOTS-Plus for MDR-TB (Member): A prioritised research agenda for DOTS-Plus for multidrug-resistant tuberculosis (MDR-TB). Int. J. Tuberc. Lung Dis. 7:410-414 (2003)
Lantos A, Niemann S, Mezosi L, Sos E, Erdelyi K, David S, Parsons LM, Kubica T, Ruesch-Gerdes S, Somoskovi A: Pulmonary tuberculosis in a captive Siberian tiger due to infection by Mycobacterium bovis subsp caprae. Emerg Infect Dis 9:1462-1464 (2003)
Sola C, Rastogi N, Gutierez MC, Vincent V, Brosch R, Parsons LM: Is Mycobacterium africanum Subtype II (Uganda I and Uganda II) a genetically well-defined subspecies of Mycobacterium tuberculosis complex: [Letter]. J Clin Microbiol 41:1345-1348 (2003)
Wang J, Parsons LM, Derbyshire KM: Unconventional conjugal DNA transfer in mycobacteria. Nature Genetics 34:80-84 (2003)
2002
Mester J, Somoskovi A, Pataki G, Parsons LM, Fodor T, Salfinger M, Vadasz I: Analysis of the year 2000 tuberculosis surveillance in Hungary. Int. J. Tuberc. Lung Dis. 6:966-973 (2002)
Larsen MH, Vilcheze C, Kremer L, Besra GS, Parsons L, Salfinger M, Heifets L, Hazbon MH, Alland D, Sacchettini JC, Jacobs WR, Jr: Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG, and M. tuberculosis. Mol. Microbiol. 2:453-466 (2002)
Witt-Kushner J, Astles JR, Ridderhof JC, Martin RA, Wilcke B, Jr, Downes FP, Inhorn SL, Kelley HP, Kimsey PB, Mills DE, Salfinger M, Shult PA, Verma MP, Becker SJ, Drabkowski DJ: Core functions and capabilities of state public health laboratories. Morbidity Mortality Weekly Report September 20, 2002 / Vol. 51 / No. RR-14
Somoskovi A, Mester J, Hale YM, Parsons LM, Salfinger M: Laboratory diagnosis of nontuberculous mycobacteria. Clin. Chest Med. 23:585-597 (2002)
Parsons LM, Brosch R, Cole ST, Somoskovi A, Loder A, Bretzel G, van Soolingen D, Hale YM, Salfinger M: Rapid and simple approach for identification of Mycobacterium tuberculosis complex isolates by PCR-based genomic deletion analysis. J. Clin. Microbiol. 40:2339-2345 (2002)
Brosch R, Gordon SV, Marmiesse M, Brodin P, Buchrieser C, Eiglmeier K, Garnier T, Gutierrez C, Hewinson G, Kremer K, Parsons LM, Pym AS, Samper S, van Soolingen D, Cole ST: A new evolutionary scenario for the Mycobacterium tuberculosis complex. PNAS (USA) 99:3684-3689 (2002)
2001
Bartfai Z, Somoskovi A, Kodmon C, Szabo N, Puskas E, Kosztolanyi L, Farago E, Mester J, Parsons LM, Salfinger M: Molecular characterization of rifampin-resistant isolates of Mycobacterium tuberculosis from Hungary by DNA sequencing and the Line Probe Assay. J. Clin. Microbiol. 39:3736-3739 (2001)
Hale YM, Pfyffer GE, Salfinger M: Laboratory diagnosis of mycobacterial infections: New tools and lessons learned. Clin. Infect. Dis. 33:834-846 (2001)
WHO Working Group on Drug Susceptibility Testing (Member): Guidelines for drug susceptibility testing for second-line antituberculosis drugs for DOTS-PLUS. WHO/CDS/TB/2001.288 (14 pages)
Somoskovi A, Hotaling JE, Fitzgerald M, O'Donnell D, Parsons LM, Salfinger M: Lessons from a proficiency testing event for acid-fast microscopy. CHEST 120:250-257 (2001)
Somoskovi A, Parsons LM, Salfinger M: The molecular basis for resistance to isoniazid, rifampin, and pyrazinamide in Mycobacterium tuberculosis. Respir. Res. 2:164-168 (2001)
Driscoll JR, Lee PA, Jovell RJ, Hale YM, Salfinger M: How and why do we fingerprint TB. RT - The Journal for Respiratory Care Practitioners: February/March, p39ff (2001)
Southwick K, Hoffmann K, Ferree K, Maillard J-M, Matthews J, Salfinger M: Cluster of tuberculosis cases in North Carolina: Possible association with atomizer reuse. Am. J. Infect. Control 29:1-6 (2001)
2000
Hale YM, Desmond EP, Jost KC, Jr., Salfinger M: Access to newer laboratory procedures: A call for action. Int. J. Tuberc. Lung Dis. 4:S171-S175 (2000)
Scientific Panel of the WHO Working Group on DOTS-Plus for MDR-TB (Member): Guidelines for establishing DOTS-PLUS pilot projects for the management of multidrug-resistant tuberculosis (MDR-TB). WHO/CDS/TB/2000.279 (95 pages)
Somoskovi A, Hotaling JE, Fitzgerald M, Jonas V, Stasik D, Parsons LM, Salfinger M: False-positive results for Mycobacterium celatum with the AccuProbe Mycobacterium tuberculosis complex assay. J. Clin. Microbiol. 38:2743-2745 (2000)
American Thoracic Society / Centers for Disease Control and Prevention / Council of the Infectious Disease Society of America [Dunlap NE, Bass J, Fujiwara P, Hopewell P, Horsburgh R, Salfinger M, Simone P]: Diagnostic standards and classification of tuberculosis in adults and children. Am. J. Respir. Crit. Care Med. 161:1376-1395 (2000)