Newborn Screening Program

If one parent has Sickle Trait (AS) and the other parent has the usual hemoglobin (AA):

For each pregnancy there is a 50% chance that the child will inherit the trait (AS) and a 50% chance that the child will have the usual kind of hemoglobin (AA).

NONE OF THE CHILDREN WILL HAVE SICKLE CELL DISEASE

If both parents have Sickle Cell Trait (AS):

For each pregnancy there is a 25% chance of inheriting the usual hemoglobin (AA), a 50% chance of inheriting Sickle Cell Trait (AS), and a 25% risk of inheriting Sickle Cell Disease (SS).

THESE CHANCES ARE THE SAME FOR EVERY PREGNANCY

If one parent has Sickle Cell Trait (AS) and the other parent has the Hemoglobin C Trait (AC):

For each pregnancy there is a 25W chance of inheriting the usual hemoglobin (AA), a 25% chance of inheriting Sickle Cell Trait (AS), a 25% chance of inheriting Hemoglobin C Trait (AC), and a 25% chance of inheriting SC Disease (SC).

THESE CHANCES ARE THE SAME FOR EVERY PREGNANCY