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Center for Bioinformatics Staff and Collaborators

Center for Bioinformatics

Staff

Randall H. Morse, Ph.D., is a research scientist and chief of the Laboratory of Developmental Genetics and Bioinformatics. His research is centered on chromatin structure and transcriptional regulation in yeast.

Ivan E. Auger is a research scientist of the Wadsworth Center's Computational Molecular Biology and Statistics Core Facility. His research interests include sequence analysis, protein structure prediction, and algorithms for Bayesian Bioinformatics.

Nilesh K. Banavali, Ph.D., is a research scientist at the Wadsworth Center. His research focuses on understanding macromolecular structure and dynamics in biological function using computational methods.

C. Steven Carmack is a computer scientist with extensive experience in computer system management.

Ye Ding, Ph.D., is a research scientist and principal investigator of the RNA Structure and Regulation group, who is currently interested in RNA structure prediction, small regulatory RNAs in eukaryotes, and RNA regulation in prokaryotes.

Alain Laederach, Ph.D., is a research scientist at the Wadsworth Center. His research focuses on understanding RNA structure and folding using both biochemical and computational approaches.

Dang, Long, Ph.D., is a post-doc whose current project focuses on the computational prediction of microRNA targets in various organisms.

Lee A. Newberg, Ph.D., is a research scientist who is using algorithmic, statistical, and mathematical combinatorics approaches to computational molecular biology. He is currently interested in using cross-species DNA multiple alignments for phylogeny and the detection of conserved regions.

Michael J. Palumbo is a research scientist in the Wadsworth Center's Computational Molecular Biology and Statistics Core Facility. His research interests include comparative genomics, sequence analysis, transcription regulation, microarray probe design, and other computationally intensive bioinformatics methods.

Andrew A. Reilly, Ph.D., is a research scientist and consultant in the Wadsworth Center's Computational Molecular Biology and Statistics Core Facility. He is currently working on Bayesian decision theory and experimental designs, measurement error models, discriminant analysis, laboratory proficiency, medical informatics, and calibration techniques.

Collaborators

Victor R. Ambros, M.D. Ph.D., University of Massachusetts Medical School. Computational prediction and experimental validation of miRNA target sites in Caenorhabditis elegans, Caenorhabditis briggsae and Drosophila melanogaster.

Keith M. Derbyshire, Ph.D., Wadsworth Center. Regulation of virulence loci of Mycobacteria tuberculosis and development of genetic approaches for validation of computational predictions.

Steve D. Hanes, Ph.D., Wadsworth Center. Uses Saccharomyces cerevisiae and Drosophila melanogaster to study genes that have homologs in higher organisms, including humans.

Charles E. Lawrence, Ph.D., Division of Applied Mathematics, Brown University. Bayesian applications to transcription regulation and identification of regulatory motifs, comparative genomics, antisense oligonucleotide and siRNA design, the composition of nucleotide sequences, and detailed analyses of several protein families.

Lee Ann McCue, Ph.D., Computational Biology & Bioinformatics, Pacific Northwest National Laboratory.

Kathleen A. McDonough, Ph.D., Wadsworth Center. Development of antisense strategy for gene inhibition in bacterial systems; analysis of cAMP-regulatory systems in Mycobacteria tuberculosis; characterization of gene expression differences between Yersinia pestisand Yersinia pseudotuberculosis.

Haydeh Payami, Ph.D., Wadsworth Center. Neurodegenerative disorders, including Parkinson's and Alzheimer's disease.

Igor B. Roninson, Ph.D., Ordway Research Institute. Rational design of siRNAs and shRNAs for RNAi.

Erasmus Schneider, Ph.D., Wadsworth Center. Rational design of trans-acting ribozymes for down-regulation of a breast cancer resistance gene.

William A. Thompson, Ph.D., Division of Applied Mathematics, Brown University. Computational methods for locating the regulatory elements directly encoded in DNA sequences.

Joseph T. Wade, Ph.D., Wadsworth Center. Transcription and its regulation in non-pathogenic Escherichia coli and pathogenic strains of Yersinia.

Rui Yi, Ph.D., Rockefeller University. Target prediction and validation of mammalian microRNAs.