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Investigators and Program Directors

Sudha Chaturvedi

Sudha Chaturvedi

Research Scientist, Wadsworth Center, Mycotic & Parasitic Diseases
Assistant Professor, School of Public Health, Biomedical Sciences

Ph.D., Fungal biology and pathogenesis (1990)
Faculty of Medicine, University of Delhi, Delhi, India

Postdoctoral Training: Fungal pathogenesis and parasite cell biology
University of Cincinnati and Yale University

E-mail: schaturv@wadsworth.org

Research Interests

Fungal pathogenesis, protein transport, & secretion mechanisms.

The focus of my laboratory is to understand fungal pathogenesis with special emphasis on Cryptococcus species (Cs). Cs, encapsulated yeast, causes infections in both healthy and immunocompromised individuals. Central to this investigation is an understanding of what gene products are required and expressed during infection and how this expression changes over time (from initial colonization to causation of disease) and space (in different cells or tissues within the host). We thus endeavor to understand, what selective pressures are acting on the pathogen in each microenvironment, what fungal factors are responsible for the host damage, and how the immune system is evaded. Another focus of my laboratory is to understand the molecular mechanisms underlying the non-classical release of oxidative proteins. Major aim of this investigation is to define how non-classically exported proteins pass through the cell membrane and cell wall, and which membrane and cell wall proteins facilitate these processes.

>> Select Publications

Contact Information

E-mail: schaturv@wadsworth.org
Phone: (518) 474-7563