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Investigators and Program Directors

Xiang Yang Chen

Xiang Yang Chen

Research Scientist, Wadsworth Center, Neural Injury & Repair
Neural Injury & Repair
Associate Professor, School of Public Health, Biomedical Sciences

Ph.D., Neurophysiology, University of Hong Kong (1990)
Postdoctoral training, Wadsworth Center, New York State Department of Health and State University of New York at Albany

E-mail: chenx@wadsworth.org

<< Research Interests

Select Publications

  • Chen, Y., Wang, Y., Chen, L., Sun, C., Chen, L., English, A.W., Wolpaw, J.R., and Chen, X.Y. (2010) H-reflex up-conditioning encourages recovery of EMG activity and H-reflexes after sciatic nerve transection and repair in rats. J. Neurosci. 30:16128-16136.
  • Chen, X.Y., Chen, Y., Wang, Y., Thompson, A., Carp, J.S., Segal, R., and Wolpaw, J.R. (2010) Reflex conditioning: A new strategy for improving motor function after spinal cord injury. Ann. NY Acad. Sci. 1198:E12-E21.
  • Carp, J.S., Tennissen, A.M., Liebschutz, J.E., Chen, X.Y., and Wolpaw, J.R. (2010) External urethral sphincter motoneuron properties in adult female rats studied in vitro. J. Neurophysiol. 104:1286-1300.
  • Thompson, A.K., Chen, X.Y., and Wolpaw, J.R. (2009) Acquisition of a simple skill: task-dependent adaptation plus long-term change in the human soleus H-reflex. J. Neurosci. 29:5784-5792.
  • Wolpaw J.R. and Chen X.Y. (2009) Operant conditioning of reflexes. In: Encyclopedia of Neuroscience (Squire, L.R., ed.) Oxford: Academic Press, vol. 7, pp. 225-233.
  • Wang, Y., Pillai, S., Wolpaw J.R., and Chen, X.Y. (2009) H-reflex down-conditioning greatly increases the number of identifiable GABAergic interneurons in rat ventral horn. Neurosci. Lett. 452:124-129.
  • Carp, J.S., Tennissen, A.M., Mongeluzi, D.L., Dudek, C., Chen, X.Y., and Wolpaw, J.R. (2008) An in vitro protocol for recording from spinal motoneurons of adult rats. J. Neurophysiol. 100:474-481.
  • Pillai, S., Wang, Y., Wolpaw, J.R., and Chen, X.Y. (2008) Effects of H-reflex up-conditioning on GABAergic terminals on rat soleus motorneurons. Eur. J. Neurosci. 28:668-674.
  • English, A., Chen, Y., Carp, J.S., Wolpaw, J.R., and Chen, X.Y. (2007) Recovery of electromyographic activity after transection and surgical repair of the rat sciatic nerve. J. Neurophysiol. 97:1127-1134.
  • Chen, X.Y., Pillai, S., Chen, Y., Wang, Y., Chen, L., Carp, J.C., and Wolpaw, J.R. (2007) Spinal and supraspinal effects of long-term stimulation of sensorimotor cortex in rats. J. Neurophysiol. 98:878-887.
  • Carp, J.S., Tennissen, A.M., Chen, X.Y., and Wolpaw, J. R. (2006) Diurnal H-reflex variation in mice. Exp. Brain Res. 168:517-528.
  • Wang, Y., Pillai, S., Wolpaw, J.R., and Chen, X.Y. (2006) Motor learning changes GABAergic terminals on spinal motoneurons in normal rats. Eur. J. Neurosci. 23:141-150.
  • Wolpaw, J.R., and Chen, X.Y. (2006) The cerebellum in maintenance of a motor skill: a hierarchy of brain and spinal cord plasticity underlies H-reflex conditioning. Learn. Mem. 13:208-215.
  • Chen, X.Y., Carp, J.S., Chen, L., and Wolpaw, J.R. (2006) Sensorimotor cortex ablation prevents H-reflex up-conditioning and causes a paradoxical response to down-conditioning in rats. J. Neurophysiol. 96:119-127.
  • Chen, X.Y., Chen, L., Chen, Y., and Wolpaw, J.R. (2006) Operant conditioning of reciprocal inhibition in rat soleus muscle. J. Neurophysiol. 96:2144-2150.
  • Carp, J.S., Tennissen, A.M., Chen, X.Y., and Wolpaw, J. R. (2006) H-reflex operant conditioning in mice. J. Neurophysiol. 96:1718-1727.
  • Chen, X.Y., Chen, Y., Chen, L., Tennissen, A.M., and Wolpaw, J.R. (2006) Corticospinal tract transection permanently abolishes H-reflex down-conditioning in rats. J. Neurotrauma 23:1743-1750.
  • Chen, Y., Chen, X.Y., Jakeman, L.B., Chen, L., Stokes, B.T., and Wolpaw, J.R. (2006) Operant conditioning of H-reflex can correct a locomotor abnormality after spinal cord injury in rats. J. Neurosci. 26:12537-12543.
  • Chen, X.Y. and Wolpaw, J.R. (2005) Ablation of cerebellar nuclei prevents H-reflex down-conditioning in rats. Learn. Mem. 12:248-254.
  • Chen, Y., Chen, X.Y., Jakeman, L.B., Schalk, G., Stokes, B.T., and Wolpaw, J.R. (2005) The interaction of a new motor skill and an old one: H-reflex conditioning and locomotion in rats. J. Neurosci. 25:6898-6906.
  • Carp, J.S., Tennissen, A.M., Chen, X.Y., Schalk G., and Wolpaw, J.R. (2005) Long-term spinal reflex studies in awake behaving mice. J. Neurosci. Methods 149:134-143.

Contact Information

Phone: 518-486-4916
Fax: 518-486-4910
E-mail: chenx@wadsworth.org