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Investigators and Program Directors

image of Yu-Fen (Kathy) Chou

Yu-Fen (Kathy) Chou

Research Scientist, Wadsworth Center
Scientific Officer, NYSTEM
Adjunct Assistant Professor, School of Public Health, Biomedical Sciences

PhD, Biomedical Engineering, University of California, Los Angeles (UCLA)
Postdoctoral Training: Center for Regenerative Medicine, Massachusetts General Hospital
Harvard Stem Cell Institute, Harvard Medical School

Email: yxc10@health.state.ny.us


Research Interests

Dr. Chou received her doctoral degree in biomedical engineering from University of California, Los Angeles and completed her postdoctoral fellowship training at Center for Regenerative Medicine in Massachusetts General Hospital and Harvard Medical School in Boston. At UCLA, Dr. Chouís research focused on biomaterials and tissue engineering for bone and cartilage regeneration. A new type of bio-conductive material, termed accelerated biomimetic apatite, was created by Dr. Chou to promote bone regeneration. Three dimensional biodegradable scaffolds incorporated with accelerated apatite and adipose tissue-derived stem cells were proven to heal critical size calvarial defects in mouse model.

Upon completion of her doctorate working on biomaterials and adult stem cells, Dr. Chou decided to extend her research interest in understanding the molecular mechanism of pluripotency in embryonic stem (ES) cells and germline stem cells. A novel stem cell line was derived by Dr. Chou from murine blastocyst embryos using a combination of bFGF, ActivinA and BIO (designated FAB-SCs). FAB-SCs are derived in the absence of LIF and BMP4, growth factors thought to be critical for the maintenance of murine ES cells. FAB-SCs display intriguing molecular and phenotypic properties. This novel blastocyst-derived stem cell line may serve as an important tool to enhance our understanding of stem cell biology.

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Contact Information

Phone: (518) 474-8969
Fax: (518) 474-5049
Email: yxc10@health.state.ny.us