Investigators and Program Directors

Select Publications

• Beauregard, A., M.J. Curcio and M. Belfort. 2008. The take and give between retrotransposable elements and their hosts. Ann. Rev. Genet. 42: 587-617.
• Maxwell, P.H. and M.J. Curcio. 2008. Incorporation of Y'-Ty1 cDNA destabilizes telomeres in Saccharomyces cerevisiae telomerase mutants. Genetics 179: 2313-7.
• Maxwell, P.H. and M.J. Curcio. 2007. Retrosequence formation restructures the yeast genome. Genes Dev. 21:3308-18.
• Curcio, M.J., Kenny, A.E., Moore, S., Garfinkel, D.J., Weintraub, M., Gamache, E.R., Scholes, D.T. 2007. S-phase checkpoint pathways stimulate the mobility of the retrovirus-like transposon, Ty1. Mol. Cell. Biol. 27: 8874-85.
• Maxwell, P.H. and M.J. Curcio. 2007. Host factors that control LTR-retrotransposons in Saccharomyces cerevisiae: implications for the regulation of mammalian retroviruses. Eukaryotic Cell. 6: 1069-1080.
• Curcio, M.J. and Belfort, M. 2007. The beginning of the end: links between ancient retroelements and modern telomerases. Proc. Natl. Acad. Sci. USA. 100: 15736-15741.
• Mou, Z., A.E. Kenny and M. J. Curcio. 2006. Hos2 and Set3 promote integration of Ty1 retrotransposons at tRNA genes in Saccharomyces cerevisiae. Genetics. 172: 2157-2167.
• Dutko, J. A., A. Schafer, A.E. Kenny, B.R. Cullen and M.J. Curcio. 2005. Inhibition of a yeast LTR-retrotransposon by human APOBEC3 cytidine deaminases. Curr. Biol. 15: 661-666.
• Maxwell, P.H., C. Coombes, A.E. Kenny, J.L. Lawler, J.D. Boeke and M.J. Curcio. 2004. Ty1 mobilizes subtelomeric Y´ elements in telomerase-negative Saccharomyces cerevisiae survivors. Mol. Cell. Biol. 24: 9887-9898.
• Scholes, D.T., A.E. Kenny, E.R. Gamache, Z. Mou and M.J. Curcio. 2003. Activation of an LTR-retrotransposon in response to telomere erosion. Proc. Natl. Acad. Sci. USA 100: 15736-15741.
• Curcio, M.J. and K. M. Derbyshire. 2003. The outs and ins of transposition: From Mu to Kangaroo. Nat. Rev. Mol. Cell Biol. 4: 821-902.
• Bryk, M., S. D. Briggs, B.D. Strahl, M. J. Curcio, C.D. Allis, and F. Winston. 2002. Set1, a factor required for methylation of histone H3, regulates rDNA silencing in Saccharomyces cerevisiae by a Sir2-independent mechanism. Curr. Biol. 12: 165-170.
• Scholes, D.T., M. Banerjee, B. Bowen and M.J. Curcio. 2001. Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics. 159: 1449-1465.
• Bryk, M., M. Banerjee, D. Conte and M.J. Curcio. 2001. The Sgs1 helicase of Saccharomyces cerevisiae inhibits retrotransposition of Ty1 multimeric arrays. Mol. Cell. Biol. 21: 5374-5388.
• Bryk, M., M. Banerjee, K.E. Knudsen, M. Murphy, D.J. Garfinkel and M.J. Curcio. 1997. Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast. Genes Dev. 11: 255-269.

Contact Information

E-mail: joan.curcio@wadsworth.org
Phone: (518) 473-6078
Fax: (518) 474-3181