Investigators and Program Directors

Select Publications

• Maxwell, P.H. and M.J. Curcio. 2007. Host factors that control LTR-retrotransposons in Saccharomyces cerevisiae: implications for the regulation of mammalian retroviruses. Eukaryotic Cell. May 11; [Epub ahead of print] PMID: 17496126.
• Curcio, M.J. and Belfort, M. 2007. The beginning of the end: links between ancient retroelements and modern telomerases. Proc. Natl. Acad. Sci. USA. 100: 15736-15741.
• Mou, Z., A.E. Kenny and M. J. Curcio. 2006. Hos2 and Set3 promote integration of Ty1 retrotransposons at tRNA genes in Saccharomyces cerevisiae. Genetics. 172: 2157-2167.
• Dutko, J. A., A. Schafer, A.E. Kenny, B.R. Cullen and M.J. Curcio. 2005. Inhibition of a yeast LTR-retrotransposon by human APOBEC3 cytidine deaminases. Curr. Biol. 15: 661-666.
• Maxwell, P.H., C. Coombes, A.E. Kenny, J.L. Lawler, J.D. Boeke and M.J. Curcio. 2004. Ty1 mobilizes subtelomeric Y' elements in telomerase-negative Saccharomyces cerevisiae survivors. Mol. Cell. Biol. 24: 9887-9898.
• Laplaza, J.M., M. Bostick, D.T. Scholes, M.J. Curcio and J. Callis, J. 2004. Saccharomyces cerevisiae ubiquitin-like protein Rub1p conjugates to cullin proteins Rtt101p and Cul3p in vivo. Biochem. J. 377: 459-467.
• Curcio, M. J. and K. M. Derbyshire. 2003. The outs and ins of transposition: From Mu to Kangaroo. Nat. Rev. Mol. Cell Biol. 4: 865-77.
• Scholes, D.T., A. E. Kenny, E.R. Gamache, Z. Mou and M.J. Curcio. 2003. Activation of an LTR-retrotransposon in response to telomere erosion. Proc. Natl. Acad. Sci. USA. In press.
• Bryk, M., S. D. Briggs, B. D. Strahl, M. J. Curcio, C. D. Allis, and F. Winston. 2002. Set1, a factor required for methylation of histone H3, regulates rDNA silencing in Saccharomyces cerevisiae by a Sir2-independent mechanism. Curr. Biol. 12: 165-170.
• Scholes, D. T., M. Banerjee, B. Bowen and M. J. Curcio. 2001. Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159: 1449-65.
• Bryk, M., M. Banerjee, D. Conte and M. J. Curcio. 2001. The Sgs1 helicase of Saccharomyces cerevisiae inhibits retrotransposition of Ty1 multimeric arrays. Mol. Cell. Biol. 21: 5374-5388.
• Conte, D. and M. J. Curcio. 2000. Fus3 controls Ty1 transpositional dormancy through the invasive growth pathway. Mol. Micro. 35: 415-427.
• Curcio, M. J., and D. J. Garfinkel. 1999. New lines of host defense: Inhibition of Ty1 retrotransposition by Fus3p and NER/TFIIH. Trends Genet. 15: 43-45.
• Lee, B.-S., Lichtenstein, C.P., Faiola, B., Rinckel, L.A., Wysock, W., Curcio, M.J. and D.J. Garfinkel. 1998. Posttranslational inhibition of Ty1 retrotransposition by nucleotide excision repair/ transcription factor TFIIH subunits Ssl2p and Rad3p. Genetics 148: 1743-1761.
• Garfinkel, D.J., Curcio, M.J. and Smith, V. (1998) Ty mutagenesis. In Methods in Microbiology: Yeast Gene Analysis, Vol. 26 (D. Fatz and T. Picknett, eds.) pp. 101-117. Academic Press, New York.
• Conte, D., Barber, E., Banerjee, M., Garfinkel, D.J. and Curcio, M.J. (1998) Posttranslational regulation of Ty1 retrotransposition by the MAP kinase, Fus3. Mol. Cell. Biol. 18: 2502-2513.
• Bryk, M., Banerjee, M., Knudsen, K.E., Murphy, M., Garfinkel, D.J. and Curcio, M.J. (1997) Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast. Genes Dev. 11: 255-269.

Contact Information

E-mail: joan.curcio@wadsworth.org
Phone: (518) 473-6078
Fax: (518) 474-3181