Main Body
Investigators and Program Directors
Laurence S. Kaminsky
Research Scientist, Wadsworth Center, Human Toxicology and Molecular Epidemiology
Professor, School of Public Health, Environmental Health Sciences
Ph.D., Chemistry, University of Cape Town (1966)
E-mail: kaminsky@wadsworth.org
Select Publications
- Bessette, E.E., Fasco M.J., Pentecost B.T., and Kaminsky, L.S. (2005). Mechanisms of arsenite-mediated decreases in benzo[k]fluoranthene-induced human cytochrome P4501A1 levels in HepG2 cells. Drug Metab. Disp. 33: 312-320, 2005.
- Wu, L., Gu, J., Cui, H., Zhang, Q.-Y, Behr, M., Fang, C., Weng Y., Kluetzman, K., Swiatek, P., Yang, W., Kaminsky, L.S., and Ding, X. (2004). Transgenic mice with a hypomorphic NADPH-cytochrome P450 reductase gene: Effects on development, reproduction, and microsomal cytochrome P450. J. Pharmacol. Expt. Ther. 312: 35-43, 2005.
- Spivack, S.D., Hurteau, G.J., Jain R., Kumar, S.V., Aldous, K.M., Gierthy, J.F., Kaminsky L.S. (2004) Gene-environment interaction signatures by quantitative mRNA profiling in exfoliated bucall mucosal cells. Cancer Res. 64:6805-6813, 2004.
- Spivack, S.D, G.J. Hurteau, M.F. Fasco, and L.S. Kaminsky (2003) Phase I and II carcinogen metabolism gene expression in human lung tissue and tumors. Clin. Cancer Res. 9, 6002-6011.
- Zhang, Q.Y., Dunbar, D., and Kaminsky, L.S. Characterization of mouse small intestinal cytochrome P450 expression. Drug Metab. Disp. 31, 1346-1351 (2003).
- Ding, X. and L.S. Kaminsky (2003) Human extrahepatic cytochromes P450: Function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts. Ann. Rev. Pharmacol. Toxicol. 43,149-173.
- Kaminsky, L.S. and Q-Y. Zhang (2003) The small intestine as a xenobiotic-metabolizing organ. Drug Metab. Disp. 31, 1520-1525.
Contact Information
Phone: (518) 474-4920
Fax: 486-1505
E-mail: kaminsky@wadsworth.org.
