Skip header information|
Wadsworth Center Home - Science in the Pursuit of Health|
NY.gov Portal State Agency Listing
Main Body

Investigators and Program Directors

Laura Kramer

Laura D. Kramer

Research Scientist, Wadsworth Center,
Zoonotic Diseases

Viral Replication and Vector Biology

Ph.D., Cornell Medical School
Postdoctoral training, University of California, Berkeley

E-mail:kramer@wadsworth.org

Research Interests

The research program of the Arbovirus Laboratories focuses on basic and applied field and laboratory studies examining the interaction of mosquito and tick-borne arboviruses, arthropod vectors, and vertebrate hosts, and how this interaction impacts transmission intensity and perpetuation of the pathogen. The research program includes studies with alpha- and flavi- viruses, examining intrinsic (genetic) and extrinsic (temperature, dose, time after infection) factors affecting vectorial capacity. Our studies are currently focusing on the flavivirus, West Nile virus (WNV), which, like all flaviviruses, is a positive sense, single-stranded RNA virus. Research addresses the molecular epidemiology of this virus over time and space, as well as that of eastern equine (EEEV; alphavirus). WNV is being studied intensively to elucidate the virus-vector interactions and viral molecular biology that led to rapid evolution in North America. Research is underway to elucidate mechanisms by which arboviruses overwinter in temperate environments, particularly EEEV in northeastern USA. Other studies are ongoing that examine factors that constrain or enhance viral evolution and adaptation to arthropod and avian hosts. In particular, the lab is focusing on the role of intrahost viral diversity and how this impacts viral fitness.

>> Select Publications

Contact Information

E-mail:kramer@wadsworth.org.