Investigators and Program Directors

David A. Lawrence

Research Scientist, Wadsworth Center, Clinical and Experimental Endocrinology and Immunology
Professor, School of Public Health, Biomedical Sciences and Environmental Health Sciences

Ph.D., Biochemistry, Boston College (1971)
Postdoctoral Training: Scripps Clinic and Research Foundation, Immunopathology (1974)

E-mail: david.lawrence@wadsworth.org

Select Publications

• Pedersen-Lane, J. R.B. Zurier, and D.A. Lawrence. (2007). Analysis of the thiol status of peripheral blood leukocytes in rheumatoid arthritis patients. J. Leukocyte Biol. 81, 934-941.
• Gao, D., T. K. Mondal, and D. A. Lawrence. In vitro effects of lead on development and function of bone marrow-derived dendritic cells. Toxicol appl Pharmacol. 222, 69-79.
• Lawrence, D.A. V. J. Bolivar, C. A. Hudson, T. Mondal, and N. G. Pabello. (2007). Antibody induction of lupus-like neuropsychiatric manifestations. J. Neuroimmunol. 182, 185-194.
• Emeny, R.T., D. Gao and D.A. Lawrence (2007). ß1 adrenergic receptors on immune cells impair innate defenses against Listeria. J. Immunol. 178, 4876-4884.
• Huber, V.C., T. K. Mondal, S.A. Factor, R.F. Seegal, and D.A. Lawrence (2006). Antibodies in the sera of Parkinson's disease patients react with neuronal membrane proteins of a mouse dopaminergic cell line and affect its dopamine expression. J. Neuroinflammation 3, 1-10.
• Pabello, N.G. and D.A. Lawrence (2006). Neuroimmunotoxicology: Modulation of neuroimmune networks by toxicants. Clin Neurosci Res 6, 69-85.
• Filipov, N.M., Seegal, R.F., and Lawrence, D.A. (2005). Manganese Potentiates In Vitro Production of Proinflammatory Cytokines and Nitric Oxide by Microglia Through a Nuclear Factor kappa B-Dependent Mechanism. Toxicol Sci. 84, 139-48.
• Mishra, N.N., S. Retterer, T. J. Zieziulewicz, M. Isaacson, D. Szarowski, D. E. Mousseau, D. A. Lawrence and J. N. Turner. (2005). On-chip micro-biosensor for the detection of human CD4⁺ cells based on AC impedance and optical analysis. Biosensor Bioelectronics 21, 696-704.
• Hudson, C.A., T.K. Mondal, L. Cao, J. Kasten-Jolly, V.C. Huber, and D.A. Lawrence (2004). The dietary supplement ephedrine induces b-adrenergic mediated exacerbation of systemic lupus erythematosus in NZM391 mice. Lupus 14, 295-307.
• Hudson, C.A., Cao, L., Kasten-Jolly, J., Kirkwood, J.N. and D.A. Lawrence (2003). Susceptibility of lupus-prone NZM mouse strains to lead exacerbation of systemic lupus erythematosus symptoms. J. Toxicol Environ. Health 66, 895-918.
• Ault, J.G. and D.A. Lawrence 2003. Glutathione distribution in normal and oxidatively stressed cells. Exp Cell Res 285, 9-14.
• Filipov, N.M., Cao, L., Seegal, R.F. and D.A. Lawrence 2002. Compromised peripheral immunity of mice injected intrastriatally with six-hydroxydopamine. J. Neuroimmunol. 132, 129-139.
• O'Neil-Andersen, N. and D.A. Lawrence. (2002). Differential modulation of surface and intracellular protein expression by T cells after stimulation in the presence of monensin or brefeldin A. Clin Diag Lab Immunol 9, 243-250.
• Cao, L. and Lawrence, D.A. 2002. Suppression of host resistance to Listeria monocytogenes by acute cold/resistant stress: lack of direct IL-6 involvement. J Neuroimmunol. 133, 132-143.
• Dyatlov V.A. and D. A. Lawrence. (2002). Neonatal lead exposure potentiates sickness behavior induced by Listeria monocytogenes infection of mice. Brain Behav Immunity 16, 477-492.
• Kim, D., Reilly, A. & Lawrence, D. A. (2000). Relationships between IFN-gamma, corticosterone and Listeria monocytogenes pathogenesis in BALB/c mice. Cellular Immunology 207, 13-18.
• Lawrence, D.A. and Kim D. 2000. Central/peripheral nervous system and immune responses. Toxicology 142:189-201.
• Rudofsky U.H. and Lawrence, D. A. 1999. New Zealand Mixed mice: a genetic systemic lupus erythematosus model for assessing environmental effects. Environ Health Perspect 107:713-721.

Contact Information

Phone: (518)402-5684
Fax: (518)-474-1412
E-mail: david.lawrence@wadsworth.org.