Main Body
Investigators and Program Directors
David LeMaster
Research Scientist, Wadsworth Center, Molecular Diagnostics
Associate Professor, School of Public Health, Biomedical Sciences
Ph.D., Yale University (1980)
Postdoctoral training, Yale University
E-mail: lemaster@wadsworth.org
Select Publications
- Hernández, G. and LeMaster, D.M. "Hybrid Native Partitioning of the Interactions among Nonconserved Residues in Chimeric Proteins", Proteins: Structure, Function, and Bioinformatics, in press
- LeMaster, D.M., Tang, J., Paredes, D.I. and Hernández, G., "Contribution of the Multi-turn Segment in the Reversible Thermal Stability of Hyperthermophile Rubredoxin: NMR Thermal Chemical Exchange Analysis of Sequence Hybrids" Biophysical Chemistry 116, 57-65 (2005).
- LeMaster, D.M., Tang, J., Hernández, G., "Absence of Kinetic Thermal Stabilization in a Hyperthermophile Rubredoxin Indicated by 40 Microsecond folding in the Presence of Irreversible Denaturation" Proteins: Structure, Function, and Bioinformatics, 57, 118-127 (2004).
- Hernández, G., and LeMaster, D.M., "Relaxation Compensation in Chemical Exchange Measurements for the Quantitation of Amide Hydrogen Exchange in Larger Proteins" Magnetic Resonance in Chemistry 41 (9):699-702 (2003).
- McNaughton, L., Hernández, G., and LeMaster, D.M., "Equilibrium O2 Distribution in the Zn2+-Protoporphyrin IX Deoxymyoglobin Mimic: Application to Oxygen Migration Pathway Analysis" Journal of the American Chemical Society 125: 3813-3820 (2003).
- Hernández, G., Teng, C-L., Bryant, R.G., LeMaster, D.M., "O2 Penetration and Proton Burial Depth in Proteins: Applicability to Fold Family Recognition" Journal of the American Chemical Society 124:4463-4472 (2002).
- Hernández, G., LeMaster, D.M., "3D Heteronuclear Long Range 1H-13C Scalar Correlation at Natural Abundance: Application to Oligosaccharide Analysis" Magnetic Resonance in Chemistry 40(3):169-174 (2002).
- Hernández, G., LeMaster, D.M., "Reduced Temperature Dependence of Collective Conformational Opening in a Hyperthermophile Rubredoxin" Biochemistry 40:14384-14391 (2001).
- Hernández, G, LeMaster, D.M., "Millisecond Time Scale Conformational Flexibility in a Hyperthermophile Protein at Ambient Temperature" Proceedings of the National Academy of Sciences 97:3166-3170 (2000).
- D. M. LeMaster, "NMR Relaxation Analysis of the Dynamics of Buried Protein Sidechains" J. Am. Chem. Soc. 121:1726-1742 (1999).
Contact Information
Phone: (518) 474-6396
Fax: (518) 473-2900
E-mail: lemaster@wadsworth.org