Investigators and Program Directors

Select Publications

• Mannella, C.A. (2008) Annals NY Acad. Sci. 1147:171-179. Structural diversity of mitochondria: Functional implications.
• Kanazawa, T., Zappaterra M.D., Hasegawa A., Wright A.P., Newman-Smith E.D., Buttle, K.F., McDonald, K., Mannella, C.A., van der Bliek, A. (2008) PLoS Genet 4(2): e1000022. doi:10.1371. The C. elegans Opa1 homologue EAT-3 Is essential for resistance to free radicals.
• Marko, M, Hsieh, C., Schalek, R. Frank, J., Mannella, C. (2007) Nature Methods, 4:215-217.Focused-ion-beam thinning of frozen-hydrated biological specimens for cryo-electron microscopy.
• Mannella, C.A. (2006) Biochim. Biophys. Acta 1762, 140-147. The relevance of mitochondrial membrane topology to mitochondrial function.
• Csordás, G., Renken, C., Várnai, P., Walter, L., Weaver, D., Buttle, K.F., Balla, T., Mannella, C.A., Hajnóczky, G. (2006) J. Cell Biol. 174, 915-921 Structural and functional features and significance of the physical linkage between ER and mitochondria.
• Celotto, A.M., Frank, A.C., McGrath, S.W., Fergestad, T., Van Voorhies, W.A., Buttle, K.F., Mannella, C.A., Palladino, M.J. (2006) J. Neurosci. 26, 810-820. Mitochondrial encephalomyopathy in Drosophila.
• Marko, M., Hsieh, C.-E., MoberlyChan, W., Mannella, C.A., Frank, J. (2006) J. Microscopy 222, 42-47. Focused ion beam milling of vitreous water: Prospects for an alternative to cryo-ultramicrotomy of frozen-hydrated biological samples.
• Hsieh, C.-E., Marko, M., Leith, A., Mannella, C.A., Frank, J. (2006) J. Struct. Biol. 153, 1-13. Towards high-resolution three-dimensional imaging of native mammalian tissue: Electron tomography of frozen-hydrated rat liver sections.
• Mannella, C.A. (2006) Biochim. Biophys. Acta 1763, 542-548. Structure and dynamics of mitochondrial inner membrane cristae.
• Keithly, J.S., Langreth, S.G., Buttle, K.F., Mannella, C.A. (2005) J. Eukaryot. Microbiol. 52, 1-9. Electron tomographic and ultrastructural analysis of the Cryptosporidium parvum relict mitochondrion, its associated membranes, and organelles.
• John, G.B., Shang, Y., Li, L., Renken, C., Mannella, C.A., Selker, J.M., Rangell, L., Bennett, M.J., Zha, J. (2005) Mol. Biol. Cell 16, 1543-1554. The mitochondrial inner membrane protein mitofilin controls cristae morphology.
• Scorrano, L., Ashiya, M., Buttle, K., Weiler S., Mannella, C.A., Korsmeyer, S.J. (2002) Devel. Cell 2, 55-67. Distinct pathways remodel mitochondrial cristae or release cytochrome c during apoptosis.
• Deng, Y., Kohlwein, S.D., Mannella, C.A. (2002) Protoplasma 219, 160-167. Fasting induces cyanide-resistant respiration and oxidative stress in the amoeba Chaos carolinensis: Implications for the cubic structural transition in mitochondrial membranes.
• Pavlov, E.V., Priault, M., Pietkiewicz, D., Cheng, E.H.-Y., Antonsson, B., Manon, S., Korsmeyer, S.J., Mannella, C.A., Kinnally, K.W. (2001) J. Cell Biol. 155, 725-732. A novel, high-conductance channel linked to apoptosis in mammalian cells and Bax expression in yeast.
• Mannella, C.A., Pfeiffer, D.R., Bradshaw, P.C., Moraru, I.I., Slepchenko, B., Loew, L.M., Hsieh, C., Buttle, K., Marko, M. (2001) IUBMB Life 52: 1-7. Topology of the mitochondrial inner membrane: dynamics and bioenergetic implications
• Frey, T., Mannella, C.A. (2000) Trends Biochem. Sci. 25, 319-324. The internal structure of mitochondria.

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E-mail: carmen@wadsworth.org

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