Randall H. Morse - Microarray Data

Microarray data from these studies can be downloaded below.

All expression data are given as log2 values, relative to wild type or indicated strain; for nucleosome occupancy data (Ganapathi et al., 2011), data are provided as log2 of nucleosome occupancy intensities relative to genomic DNA.

Data from Ansari et al. (2011) includes log2 values of expression of gal11(med15)∆ med2∆ yeast and gal11-myc med2∆ yeast compared to wild type, grown in YPD and in CSM.

Data from Ganapathi et al. (2011) includes data for nucleosome occupancy using Affymetrix tiling arrays (PN520055) of abf1 ts and the corresponding wild type yeast after one hour growth in YPD at 37˚C, and of rap1 ts and the corresponding wild type yeast after one hour growth in YPD at 37˚C.  Two additional files provide comparisons between nucleosome occupancy in abf1 ts and wild type yeast, and rap1 ts and wild type yeast.  Each “.bar” file represents averaged data from three independent experiments.  The “.bed” files contain regions showing significant change in nucleosome occupancy between wild type and ts mutant, as described in Ganapathi et al. (2011).

Data from Yu et al. (2006) includes comparison of H31-28 to wild type yeast, and H42-26 to wild type yeast, all grown in Complete Synthetic Medium (CSM). We also include comparison of wild type yeast grown in YPD and CSM.

Data from Yarragudi et al. (2007) includes comparison of abf1 ts yeast to wild type at 37 C, and rap1 ts yeast to wild type at 37 C, all grown in YPD (rich medium).

The information in Tables 2 and 3 from Sabet et al. (2003) can be downloaded from this site as Microsoft Excel files. Table 2 contains microarray data comparing gene expression from H3Δ1-28 yeast cells to wild type; three comparisons are included. Table 3 contains microarray data comparing gene expression from H4Δ2-26 to wild type yeast cells. Comparisons between two H4Δ2-26 samples and two wild type samples are shown.

Data from Sabet et al. (2004) can also be downloaded as a single Excel file that includes comparisons of H3Δ1-28, H4Δ2-26, H3(K4,9,14,18,23,27Q), H4(K5,8,12,16Q), and rpd3Δ to wild type, and also rpd3Δ H3Δ1-28 to H3Δ1-28 and rpd3Δ H4(K5,8,12,16Q) to H4(K5,8,12,16Q).

CEL files for all experiments have been deposited in the Gene Expression (GEO) website; see publications for accession numbers

To save the following Excel files, right click on a PC or Unix workstation, or click on a Macintosh, and select "Save as". In most browsers, these files can be directly viewed simply by clicking. To view, open in Excel. The Ganapathi files are .bar files; these files are viewable using the Integrated Genome Browser (IGB) or similar software.

If you need these files in an alternative format, please contact us below.

• Ansari et al. (2011), (Excel -- 1.3M )
• Yu et al. microarray data (Excel -- 3.3M )
• Yarragudi et al. microarray data (Excel -- 3.0M)
• H3 (Table 2) (Excel -- 1.8M)
• H4 (Table 3) (Excel -- 1.1M)
• Sabet et al. (2004) (Excel -- 2.1M)
• Ganapathi et al. (2011)

CONTACT INFORMATION

Phone: 518-486-3116
Fax: 518-402-2299
E-mail: morse@wadsworth.org.