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Investigators and Program Directors

Janice Pata

Janice Pata

Research Scientist, Wadsworth Center,
Computational & Structural Biology
Assistant Professor, School of Public Health, Biomedical Sciences

Postdoctoral training, Yale University
Ph.D., University of Colorado at Boulder
B.S., California Institute of Technology

Email: jpata@wadsworth.org

<< Research Interests

Select Publications

  • Pata JD, Stirtan WG, Goldstein SW, and Steitz TA (2004) Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors. PNAS 101:10548-10553. PubMed
  • Pata JD, King BR, Steitz TA (2002) Assembly, purification and crystallization of an active HIV-1 reverse transcriptase initiation complex. Nucleic Acids Research 30: 4855-4863. PubMed
  • Zhou BL, Pata JD, Steitz TA (2001) Crystal structure of a DinB lesion bypass DNA polymerase catalytic fragment reveals a classic polymerase catalytic domain. Molecular Cell 8:427-437. PubMed
  • Jäger J, Pata JD (2001) Viral RNA-directed polymerases. In: Structure-function Relationships of Human Pathogenic Viruses. E. Bogner and A. Holzenburg, Editors, Kluwer Academic Press, Plenum Publishers. Chapter 2, pages 53-84.
  • Jäger J, Pata JD (1999) Getting a grip: polymerases and their substrate complexes. Current Opinion in Structural Biology 9:21-28. PubMed
  • Pata JD, Schultz SC, Kirkegaard K (1995) Functional oligomerization of poliovirus RNA-dependent RNA polymerase. RNA 1:466-477. PubMed

Editorials Describing Our Work

Contact Information

Office: 518-402-2595
Lab: 518-402-4673
FAX: 518-402-4623
Email: jpata@wadsworth.org

Mailing address:
Wadsworth Center
New York State Department of Health
P.O. Box 509
Albany, NY 12201-0509

Street address:
Center for Medical Sciences
150 New Scotland Avenue
Albany, NY 12208