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Investigators and Program Directors

image of William Shain, Phd

William Shain, Phd

Research Scientist, Wadsworth Center, Translational Medicine
Center for Neural Communication Technology

School of Public Health, Biomedical Sciences
Environmental Health Sciences

Ph.D., Temple University, (1972)
Postdoctoral training, National Institutes of Health

E-mail: shain@wadsworth.org

<< Research Interests

Select Publications

    • Bjornsson, C.S., S.J. Oh, Y.A. Al-Kofahi; Y.J. Lim, K.L. Smith, J.N. Turner, S. De B. Roysam W. Shain, S.J. Kim (2006) Shape- and Insertion Speed-Dependent Tissue Damage due to Neuroprosthetic Device Insertion. J Neural Eng. 3, 196-207.
    • Wolpaw, J.R., G.E. Loeb, B.Z. Allison, Williams JC, J Hippensteel, J Dilgen, W Shain, DR Kipke (2007) Complex impedance spectroscopy of monitoring tissue responses to inserted neural implants, J Neural Engin 4:410-423.
    • Frampton, JP, MR Hynd, JC Williams, ML Schuler, W Shain (2007) Three-dimensional hydrogel cultures for modeling changes in tissue impedance around microfabricated neural probes, J Neural Engin, 4:399-409
    • Jun SB, MR Hynd, NM Dowell-Mesfin, Y Al-Kofahi, B Roysam, W Shain, SJ Kim (2008) Modulation of cultured neural networks using neurotrophin release from hydrogel-coated microelectrode arrays. J Neural Engin 5:203-13.
    • Bjornsson, CS, G Lin, Y Al-Kofahi, A Narayanaswamy, KL Smith, W Shain, B Roysam (2008) Associative image analysis: A method for automated quantification of 3D multi-parameter images of brain tissue. J Neurosci Meth 170:165-178.
    • Retterer, ST, KL Smith, CS Bjornsson, JN Turner, SM Isaacson, W Shain (2008) Constant pressure fluid infusion into rat neocortex from implantable microfluidic devices, J Neural Eng 5:385-391.
    • Kipke, DR, W Shain, G Buzsáki, E Fetz, J Henderson, J Hetke, G Schalk (2008) Advanced neurotechnologies for chronic neural interfaces: New horizons and clinical opportunities, J Neruorsci, 28:11830-11838.
    • Roysam, B, W Shain, GA Ascoli (2008) The central role of neuroinformatics in the National Academy of Engineering's Grandest Challenge: Reverse Engineer the Brain, Neuroinformatics 7:1-5.
    • Jhaveri SJ, MR Hynd, N Dowel-Mesfin, JN Turner, W Shain, CK Ober (2009) The release of nerve growth factor from HEMA hydrogel coated substrates and its effect on the differentiation of neural cells, Biomacromol 10:174-183.

Contact Information

Phone: (518)473-3630
Fax: (518)474-7466
E-mail: shain@wadsworth.org.