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Investigators and Program Directors

David Wentworth

David E. Wentworth

Research Scientist, Wadsworth Center, Microbial Genetics
Assistant Professor, School of Public Health, Biomedical Sciences

Ph.D., University of Wisconsin-Madison
Postdoctoral training, University of Colorado Health Sciences Center

E-mail: dwentwor@wadsworth.org

<< Research Interests

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  • Wentworth, D. E., D. B. Tresnan, B. C. Turner, I. R. Lerman, B. Bullis, E. M. Hemmila, R. Levis, L. H. Shapiro, and K. V. Holmes. 2005. Cells of human aminopeptidase N (CD13) transgenic mice are infected by human coronavirus-229E in vitro, but not in vivo. Virology 335:185-197. PubMed
  • Jeffers,S.A., Tusell,S.M., Gillim-Ross,L., Hemmila,E.M., Achenbach,J.E., Babcock,G.J., Thomas,W.D., Jr., Thackray,L.B., Young,M.D., Mason,R.J., Ambrosino,D.M., Wentworth,D.E., Demartini,J.C., and Holmes,K.V. (2004). CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus. Proc. Natl. Acad. Sci. U.S.A. 101, 15748-15753. PubMed
  • Wentworth,D.E., Gillim-Ross,L., Espina,N., and Bernard,K.A. (2004). Mice susceptible to SARS coronavirus. Emerging Infectious Diseases 10, 1293-1296. PubMed
  • Gillim-Ross,L., Taylor,J., Scholl,D.R., Ridenour,J., Masters,P.S., and Wentworth,D.E. (2004). Discovery of novel human and animal cells infected by the severe acute respiratory syndrome coronavirus by replication-specific multiplex reverse transcription-PCR. J Clin Microbiol 42, 3196-3206. PubMed
  • Bonavia, A., B.D. Zelus, D.E. Wentworth, P.J. Talbot, and K.V. Holmes. 2003. Identification of a receptor-binding domain of the spike glycoprotein of human coronavirus HCoV-229E. Journal of Virology. 77 (4):2530-2538. PubMed
  • Wentworth, D.E. and K.V. Holmes. 2001. Molecular determinants of species specificity in the coronavirus receptor aminopeptidase N (CD13): influence of N-linked glycosylation. Journal of Virology. 75(20):9741-9752. PubMed
  • Wentworth, D.E. and K.V. Holmes. 2001. Addition of a single glycosylation site to hAPN blocks human coronavirus-229E receptor activity. Adv Exp Med Biol 494:199-204. PubMed
  • Schickli, J., D.E. Wentworth, B.D. Zelus, K.V. Holmes, and S.G. Sawicki. 1998. Selection in persistently infected murine cells of an MHV-A59 variant with extended host range. Adv Exp Med Biol 440:735-741. PubMed
  • Schickli, J., B.D. Zelus, D.E. Wentworth, S.G. Sawicki, and K.V. Holmes. 1997. Murine coronavirus mouse hepatitis virus strain A59 from persistently infected murine cells exhibits an extended host range. Journal of Virology. 71:9499-9507. PubMed
  • Wentworth, D. E., M. W. McGregor, M. D. Macklin, V. Neumann, and V. S. Hinshaw. 1997. Transmission of swine influenza virus to humans after exposure to experimentally infected pigs. Journal of Infectious Diseases 175:7-15. PubMed
  • Wentworth, D. E., B. L. Thompson, X. Xu, H. L. Regnery, A. J. Cooley, M. W. McGregor, N. J. Cox, and V. S. Hinshaw. 1994. An influenza A (H1N1) virus, closely related to swine influenza virus, responsible for a fatal case of human influenza. Journal of Virology 68:2051-2058. PubMed
  • Schorr, E., D. Wentworth, and V. S. Hinshaw. 1994. Use of polymerase chain reaction to detect swine influenza virus in nasal swab specimens. American Journal of Veterinary Research 55:952-956. PubMed
  • Noble, S., M. S. McGregor, D. E. Wentworth, and V. S. Hinshaw. 1993. Antigenic and genetic conservation of the haemagglutinin in H1N1 swine influenza viruses. Journal of General Virology 74:1197-1200. PubMed
  • Hinshaw, V. S., B. C. Easterday, M. W. McGregor, D. Wentworth, and G. Early. 1992. Interspecies transmission of influenza A viruses. Proc. 3rd International Symp. on Avian Influenza 106-109.

Contact Information

E-mail: dwentwor@wadsworth.org.

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