Resource for the Visualization of Biological Complexity (RVBC)
Electron microscopes
Three electron microscopes are associated with the RVBC:
IVEM: JEOL
JEM-4000FX Intermediate-voltage electron
microscope
Our IVEM is the only 400keV energy-filtered TEM that is
specifically configured for low-dose electron tomography of
frozen-hydrated specimens, which is its main application.
It also has full microanalytical capability. (IVEM: JEOL
JEM-4000FX Intermediate-voltage details...)
HVEM: AEI EM-7 Mk II High-voltage electron
microscope
Our HVEM, with a maximum accelerating voltage of 1200keV,
is one of only two HVEMs worldwide that are dedicated to
biological applications. It is primarily used for electron
tomography of thick plastic sections. (HVEM: AEI EM-7 Mk II High-voltage electron
microscope details...)
F20: FEI Tecnai TF-20 Field-emission gun
cryo-electron microscope
Our F20 is a 200keV TEM that is used primarily for
acquiring data for single-particle reconstruction of
macromolecules. It is also used for electron tomography of
thin specimens. (F20: FEI Tecnai TF-20 Field-emission gun
cryo-electron microscope details...)
Other electron microscopes at Wadsworth
Center
The Biggs Laboratory at the Empire State Plaza currently
houses five electron microscopes in addition to the RVBC
microscopes. Some of these microscopes may be used for
certain RVBC-related projects. (details...)

