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3-D Electron Microscopy Group

Mission

The 3D-EM group at Wadsworth develops advanced methods of three-dimensional imaging with the electron microscope to look at different levels of biological architecture.  Their aim is to integrate this new structural knowledge with existing data to achieve a comprehensive understanding of the structure and dynamics of biological systems.  Single-particle reconstructions methods are used to study macromolecular interactions in isolated, well-characterized systems, while electron tomography provides detailed 3D information about cellular ultrastructure.

3D-EM Group

Dr. Rajendra Agrawal
agrawal@wadsworth.org
518-486-5797

Dr. ArDean Leith
leith@wadsworth.org
518-486-5604

Dr. Zheng Liu
liuz@wadsworth.org
518-486-2712

Dr. Carmen Mannella
carmen@wadsworth.org
518-474-2462

Mr.Michael Marko
marko@wadsworth.org
518-474-7049

Dr.Bruce McEwen
bruce@wadsworth.org
518-486-9102

Dr. Tapu Shaikh
tapu@wadsworth.org
518-474-6516

Dr. Haixin Sui
hsui@wadsworth.org
518-474-4235

Dr.Terence Wagenknecht   
terry@wadsworth.org
518-474-2450

Scientific Staff

Mr. David Barnard - HVEM facility, instrument development, time-resolved cryo-EM

Ms. Chyongere Hsieh - Cryo-electron tomography, cryo-preparation, frozen-hydrated sections

Mr. David Mankus – EM tomography and visualization

Dr. Xing Meng – Cryo-electron tomography, cryo-preparation

3D-EM facility use

Individuals interested in conducting 3D-EM research at the Wadsdworth Center may contact any of the 3D-EM group to discuss collaboration and fee-for-service use of the facilities.