Resource for the Visualization of Biological Complexity (RVBC)
Mission
The mission and long-term goal of the RVBC is twofold: (1) to develop tools for visualization of biological systems in their entirety, in close to native conditions, and (2) to make this technology, when firmly established and tested, available to the scientific community. We are making use of advanced methods of three-dimensional imaging with the electron microscope and computation to look at different levels of biological architecture, and aim to integrate the knowledge gained from these experiments with existing data towards a comprehensive understanding of biological systems - their structure and dynamics. While single-particle reconstructions methods are used to study macromolecular interactions in isolated, well-characterized systems, electron tomography provides a detailed picture of the cell in its entirety.
Executive Committee
| Dr. Joachim Frank | joachim@wadsworth.org | 518-474-7002 |
| Dr. Carmen Mannella | carmen@wadsworth.org | 518-474-2462 |
| Mr. Michael Marko | marko@wadsworth.org | 518-474-7049 |
| Dr. Bruce McEwen | bruce@wadsworth.org | 518-486-9102 |
| Dr. Terence Wagenknecht | terry@wadsworth.org | 518-474-2450 |
Scientific Staff Members
| Mr. David Barnard | HVEM facility, instrument development, time-resolved cryo-EM |
| Dr. William Baxter | SPIDER development, SPIRE (reconstruction engine) |
| Ms. Karolyn Buttle | HVEM tomography, time-resolved cryo-EM |
| Ms. Chyongere Hsieh | Cryo-tomography, cryo-preparation, frozen-hydrated sections |
| Dr. Ardean Leith | SPIDER and WEB maintenance and development, visualization |
| Dr. Bimal Rath | SPIDER and WEB development, motif and particle search |
| Dr. Christian Renken | Cryo-tomography: algorithm development, motif search |
| Dr. Tapu Shaikh | Single-particle EM: algorithm development, time-resolved cryo-EM |
Administrative Assistant, mailing address
-
Ms. Shawna-Kay Addison
Resource for Visualization of Biological Complexity
Wadsworth Center
P.O. Box 509
Albany, NY 12201-0509
- Tel: 518-474-7002
- Fax: 518-486-2191
RVBC facility use
Individuals interested in using the facility may contact the RVBC Director, Dr. Joachim Frank. The application form is available as an (Adobe .pdf file) or (word file) and should be emailed to the Administrative Assistant for review by the Executive Committee.
