New York State Department of Health, Wadsworth Center
Published on New York State Department of Health, Wadsworth Center (https://www.wadsworth.org)

Home > Nicholas J. Mantis, Ph.D.

Nicholas J. Mantis, Ph.D. [1]

Nicholas J. Mantis, Ph.D. [2]
Chief, Microbial Pathogenesis and Immunology
Professor, Department of Biomedical Sciences, School of Public Health, University at Albany
Mucosal Immunology
Ph.D., Cornell University
Postdoctoral Fellow and Fulbright Scholar, Pasteur Institute in Paris, Children’s Hospital Boston, and Harvard Medical School
E-mail: 
nicholas.mantis@health.ny.gov [3]
Phone: 
(518) 473-7487
Fax: 
(518) 402-4773
The mucosal immune system produces secretory IgA antibodies that protect epithelial surfaces from toxins and microbial patho
Scanning electron micrographs of Salmonella treated with a neutralizing antibodies Sal4. Control bacteria
Scanning electron micrographs of Salmonella treated with a neutralizing antibodies Sal4. Bacteria treated with Sal4.
Oral ingestion of ricin toxin causes damage to the intestinal epithelium.

Dr. Mantis’ research focuses on host-pathogen interactions and the development of vaccines for biodefense and emerging infectious diseases (BDEID). His primary interest is in the role of antibodies in conferring immunity to airborne, foodborne and vectorborne infections. The laboratory has ongoing collaborations with academic and biopharmaceutic partners to develop vaccines and monoclonal antibodies for human use against COVID-19, Lyme disease, pertussis, tetanus, Salmonella, cholera, and ricin toxin.

 

Dr. Mantis has received research awards from the:

  • National Institute of Allergy and Infectious Diseases (NIAID)
  • National Institute of Child Health and Human Development (NICHD)
  • National Cancer Institute (NCI)
  • National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) Department of Defense (DOD)
  • Bill and Melinda Gates Foundation (BMGF).

For more information, please visit our webpage. 


Source URL (modified on 01/28/2021 - 12:35pm): https://www.wadsworth.org/senior-staff/nicholas-mantis

Links
[1] https://www.wadsworth.org/senior-staff/nicholas-mantis
[2] https://www.wadsworth.org/sites/default/files/mantis_nicholas_1.jpg
[3] mailto:nicholas.mantis@health.ny.gov