Dr. Styer’s research interests include the development of new molecular diagnostic tests for the detection, quantification, or characterization of bloodborne viruses and the evaluation of FDA approved diagnostic tests and diagnostic testing algorithms.

We study copy number variants (CNVs), which are widespread in the human genome and alter dosage of genes important in conditions ranging from HIV susceptibility to autism spectrum disorders. We seek to compile a catalog of CNVs and their frequencies.

Screening has uncovered individuals whose sweat chloride values are above normal, but no other CF symptoms are identified. Our aim is to determine if other variants in the CFTR gene, or modifier genes, correlate with these abnormal levels.

We study gene regulation in bacteria, with a focus on genome-scale approaches. We are interested in regulation of transcription, the function of non-coding RNAs, and leaderless translation initiation.