Published on New York State Department of Health, Wadsworth Center (https://www.wadsworth.org)

Karen J. Chave, PhD

Karen J. Chave
Director, Protein Expression and Biochemistry Cores
Research Scientist, Scientific Core
PhD: University of Surrey (1997)
Postdoctoral training: New York State Department of Health, Wadsworth Center

I am the Director of the Wadsworth Center Protein Expression Core. This core performs recombinant expression and purification of proteins in E. coli, insect and mammalian expression systems. I have over 30 years of experience in the field and specialize in finding conditions for expression of soluble protein in E. coli. I have expressed and purified over 170 proteins. 


I also direct the Wadsworth Center Biochemistry Core. This core provides instrumentation for the analysis of biomolecules and complexes. Core staff help investigators design experiments, collect, analyze and interpret data.


I am the section head for Blood pH and Gases, Clinical Chemistry, Endocrinology, and Therapeutic Substance monitoring/Quantitative Toxicology for the Clinical Laboratory Evaluation Program.  I review lab developed tests, Certificate of Qualification applications, and act as a subject matter expert.
 

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