Published on New York State Department of Health, Wadsworth Center (https://www.wadsworth.org)

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The Wadsworth Center Develops and Validates a New Method for the Analysis of Drugs in Urine from Overdose Patients [5]

Fatal drug poisoning (“overdose”) is a growing public health crisis in the United States. According to the United States National Vital Statistics System, 105,007 drug overdose deaths occurred in 2023. Whereas opioids (including prescription opioids, heroin, fentanyl and analogs) were the leading cause of overdose deaths, the pharmacological composition of drugs has evolved into a “polysubstance death” crisis.  

The Wadsworth Center’s Dr. Denise Kay Discusses Complexities of Cystic Fibrosis Genetic Analysis at the North American Cystic Fibrosis Conference [8]

Dr. Denise Kay, Director of the New York State Newborn Screening Program at the Wadsworth Center, was invited to present at the 2025 North American Cystic Fibrosis Conference, held October 22–25 in Seattle, Washington.

Wadsworth Center Staff to Serve on the Association of Public Health Laboratories’ Overdose Biosurveillance Task Force [11]

Dr. Kurunthachalam Kannan from the Division of Environmental Health Sciences (DEHS) at the Wadsworth Center, has been invited to serve on the Overdose Biosurveillance Task Force (OBTF), an advisory group charged by the Association of Public Health Laboratories (APHL) Board of Directors to provide subject matter expertise and input into the creation, dissemination, and promotion of resources for public health laboratories developing and conducting overdose biosurveillance programs in response to the evolving overdose epidemic. 

Recent Wadsworth Center Study Highlights Advancements in Detecting Trace Levels of Uranium and Plutonium in Drinking Water [17]

The Safe Drinking Water Act sets stringent standards for the detection of radioactive contaminants in public water systems. A new study from the Wadsworth Center’s Nuclear Chemistry Laboratory explores how these requirements might be exceeded through improved analytical sensitivity.

Wadsworth Center’s Mycobacteriology Laboratory Provides Critical Testing for Texas Drug-Resistant Tuberculosis Case [20]

The Wadsworth Center’s Mycobacteriology Laboratory was contacted by the Texas Department of State Health Services to perform drug susceptibility testing for a transplant recipient previously treated for pre-extensively drug-resistant (XDR) tuberculosis beginning in 2022. After nine months of therapy, the patient was initially deemed cured following a treatment regimen consisting of bedaquiline, pretomanid, and linezolid (BPaL)—currently the standard for managing multidrug- and extensively drug-resistant tuberculosis (MDR/XDR-TB).

Wadsworth Center Showcases Its Continued Leadership in Advancing Newborn Screening Science and Practice [26]

The Association of Public Health Laboratories (APHL) held its annual Newborn Screening Symposium from October 5–9 in Providence, Rhode Island, bringing together approximately 570 scientists and healthcare professionals from across the United States and around the world. The symposium addressed a broad range of topics critical to public health newborn screening systems, including enhanced biochemical and molecular screening technologies; methods for detecting new conditions; quality improvement initiatives; strateg

Wadsworth Center’s Dr. Joseph Orsini Receives George Cunningham Visionary Award in Newborn Screening [29]

Dr. Joseph Orsini, Deputy Director of the Newborn Screening Program at the Wadsworth Center, has been honored with the 2025 George Cunningham Visionary Award in Newborn Screening. This prestigious lifetime achievement award recognizes individuals working in U.S.

Wadsworth Center’s Mycology Laboratory Contributes Rare Yeast MALDI Library to CDC’s MicrobeNet Global Database [32]

The Wadsworth Center’s Mycology Laboratory has developed an in-house MALDI-TOF MS (matrix-assisted laser desorption ionization - time of flight mass spectrometry) library comprising rare yeast species, which is now one of the contributed databases available through the CDC’s MicrobeNet platform.

The Wadsworth Center’s Division of Environmental Health Sciences’ novel research paper links poor semen quality to pesticide exposure [35]

Approximately half of all cases of reported infertility in the United States involve malefactor, which is commonly diagnosed via standardized analysis of semen quality parameters that include sperm concentration, motility, and morphology.  

New York State Landmarks Illuminated in Red for Sickle Cell Awareness [38]

The New York State Newborn Screening Program housed at the Wadsworth Center was the first program in the U.S. to implement screening for sickle cell disease in 1975. Sickle cell disease is an inherited blood disorder affecting hemoglobin, the major protein that carries oxygen in red blood cells. The abnormal hemoglobin causes sickle-shaped red blood cells that can break down prematurely and/or block blood flow, leading to anemia, pain, infections, and other severe complications. Sickle cell disease affects more than 100,000 people in the U.S.

Wadsworth Scientists Graduate from APHL Emerging Leader Program [50]

In August, Brooke Clemons of the Parasitology Laboratory and Kiran Mall of the Protein Expression and Biochemistry Core Laboratories graduated from the Association of Public Health Laboratories (APHL) Emerging Leader Program (ELP), Cohort 18.  They were selected as two of 25 participants nationwide for this yearlong program designed to cultivate leadership skills among laboratory professionals from state and local public health laboratories.  

Strengthening Public Health Readiness and Building Statewide Capacity through Threat-Agnostic Sequencing [53]

The Wadsworth Center Biodefense Laboratory has been awarded $125,000 to develop, optimize, and validate threat-agnostic sequencing workflows for the rapid detection of pathogens in respiratory and other specimens. This project represents a critical step in strengthening New York State’s laboratory readiness and capacity to respond to infectious disease threats.  The initiative will integrate metagenomic and targeted sequencing methods with the Johns Hopkins University Applied Physics Laboratory Basestack software, including its TaxTriage module. 

Wadsworth Center’s Dr. Norma Tavakoli Presents at Congenital Cytomegalovirus Public Health and Policy Conference [56]

Minneapolis, MN | September 7-9, 2025 – Dr. Norma Tavakoli, PhD, of the Wadsworth Center was a featured speaker at the Congenital Cytomegalovirus (cCMV) Public Health and Policy Conference, hosted by the University of Minnesota.  Her presentation, “A Pilot Study in New York State to Screen Newborns for Congenital Cytomegalovirus,” highlighted groundbreaking work conducted by the New York State Newborn Screening Program.  

New York’s Wadsworth Center Newborn Screening Program is First in the United States to Implement Screening for Metachromatic Leukodystrophy (MLD) [59]

The New York State Newborn Screening Program at the Wadsworth Center has become the first program in the United States to implement universal newborn screening for Metachromatic Leukodystrophy (MLD), a devastating but now treatable lysosomal storage disorder.  MLD is caused by low or absent activity of the arylsulfatase A (ARSA) enzyme, leading to toxic accumulation of sulfatides and progressive damage to the nervous system.