We focus on the development and validation of assays to detect pathogens and toxins associated with bioterrorism or food-borne disease. We utilize methods such as real-time PCR, whole genome sequencing, and mass spectrometry for rapid detection of agents.

We are interested in the mechanisms underlying resistance of M. tuberculosis to major TB drugs and in the development and validation of molecular assays involving whole genome sequencing for rapid detection of drug resistant tuberculosis.

We focus on method development of radiochemical analyses for use in routine and emergency response scenarios.

Mr. Fayo oversees 8 distinct laboratory sections, the Environmental Monitoring/Public Health Testing program, the Proficiency Testing Validation program, and over 60 specialized EPA (or EPA derived) methodologies.

We study transcriptional reprogramming and regulatory networks in mycobacteria controlling resistance to genotoxic stress, hypoxia, nutrient starvation and exposure to antibiotics.

The Division of Laboratory Operations oversees the Wadsworth Center's operations at five facilities in the Albany area, totaling ~900,000 square feet of space and over 210 acres of real estate.

We use innovative molecular genomic approaches to address fundamental questions of mycobacterial biology. Our findings shed new light on the evolution and function of mycobacterial genomes, accelerating tuberculosis research.

We use a variety of techniques to develop and validate rapid methods for the detection of waterborne pathogens, or their indicators, prior to the outbreak of disease. 

Biomonitoring of human exposure to environmental chemicals; biomarkers of health effects; sources and pathways of human exposure; environmental distribution, food chain transfer and fate of organic pollutants; consumer product analysis; overdose and wastewater surveillance

We screen infants born in New York State for more than 50 conditions at birth and study the genetics of diseases affecting infants and children. 

We seek to reveal the molecular mechanisms that enact error-free segregation of chromosomes during cell division. Advanced microscopy and laser ablations allow us to probe the behavior of individual chromosomes and spindle poles.

We conduct multidisciplinary research to understand water and indoor and outdoor air pollution and their impact on human health.

The Transgenic and Gene Knockout Core produces and analyzes transgenic and gene knockout mice that can be used as animal models of human disease.

The Tissue Resources Program oversees all tissue banking activities and services provided in New York State, from donor solicitation to clinical use.

My specific area of expertise within the Bioinformatics Core is bacterial genomics, evolution and phylogeny.

My research focuses on clarifying the phylogenetic relationships among microbial organisms and understanding microbial genome evolution, including the contributions of horizontal gene transfer and endosymbioses to shaping genomes and accelerating adaptive evolution.

We study the immunological aspect of the system biology effects from genetic susceptibilities and environmental stress defined as the exposome on autoimmune diseases, immune deficiencies, and neurodegenerative and neurobehavioral illnesses.

The goal of our research is to characterize the differences between antigenically naive (virgin) and memory T helper cells at the developmental, phenotypic and functional levels.

Our work strives to further the knowledge of the mechanisms behind mucosal immune alterations that can lead to food allergies and malnutrition.

My laboratory develops improved methods of detecting, identifying and characterizing parasites that infect humans, as well as investigating pathogenicity and sources of infection.