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Christina Egan, Ph.D.

  • Christina Egan

    Christina Egan, Ph.D.

    • Director of the Biodefense Laboratory
    • Research Scientist, Wadsworth Center
    • Faculty Member and Directory of Scientific Education, Wadsworth School of Laboratory Sciences
    • Assistant Professor, School of Public Health, Biodefense

    • Ph.D., Albany Medical College, Albany, NY
    • Postdoctoral training: Albany Medical Center
    • Postdoctoral training: New York State Department of Health, Wadsworth Center

    christina.egan@health.ny.gov
    (518) 473-6900
    Fax: (518) 486-7971

  • Laboratory personnel performing analysis of bacterial colonies isolated from an Environmental sample.
    Laboratory personnel performing analysis of bacterial colonies isolated from an Environmental sample.

Research Interests

The ability to rapidly detect and respond to the intentional release of pathogens and toxins is vital in protecting the health and well-being of New Yorkers. The intentional release of Bacillus anthracis through the US Postal Service in 2001 highlighted the need for improved diagnostics in the field of Biodefense. Research at the Biodefense Laboratory focuses on the development of diagnostics for the detection of biothreat agents using platforms such as real-time PCR, DNA sequencing, and microsphere immunoassay and nucleic acid arrays.

Characterization and identification of biothreat agents is performed through analysis of multiple and varied sample types such as clinical specimens, food, water, powders, and other environmental samples. Often, these samples can be difficult to test and specialized protocols are necessary in order to perform nucleic acid testing. This work includes the development and validation of assays that can detect agents such as C. botulinum neurotoxins, Staphylococcal enterotoxins, Orthopoxviruses, Francisella tularensis, Brucella spp. Bacillus anthracis, Ricin toxin, and Yersinia pestis in different samples types in a multiplex format. Additional interests include the evaluation of biothreat samples.

In addition to serving as the Director of the Biodefence Laboratory at Wadsworth, Dr. Egan serves as Faculty Member and as the Director of Scientific Education, at the Wadsworth School of Laboratory Sciences.

Select Publications

de Bruin OM, Chiefari A, Wroblewski D, Egan C, Kelly-Cirino CD.
A novel chemical lysis method for maximum release of DNA from difficult-to-lyse bacteria.
Microb Pathog.
(2018)
126
292-297.
Ryan CW, Bishop K, Blaney DD, Britton SJ, Cantone F, Egan C, Elrod MG, Frye CW, Maxted AM, Perkins G.
Public health response to an imported case of canine melioidosis.
Zoonoses Public Health.
(2018)
65
(4):
420-424.
Perry MJ, Centurioni DA, Davis SW, Hannett GE, Musser KA, Egan CT.
Implementing the Bruker MALDI Biotyper in the Public Health Laboratory for C. botulinum Neurotoxin Detection.
Toxins (Basel).
(2017)
9
(3):
pii: E94.
Chiefari AK, Perry MJ, Kelly-Cirino C, Egan CT.
Detection of Staphylococcus aureus enterotoxin production genes from patient samples using an automated extraction platform and multiplex real-time PCR.
Mol Cell Probes.
(2015)
29
(6):
461-467.
Hannett GE, Schaffzin JK, Davis SW, Fage MP, Schoonmaker-Bopp D, Dumas NB, Musser KA, Egan C.
Two cases of adult botulism caused by botulinum neurotoxin producing Clostridium baratii.
Anaerobe.
(2014)
30
178-180.