Image of COVID-19, courtesy of the CDC

Lessons from the wastewater surveillance program initiated in early 2020, and expanded in 2022 to include sequencing the virus that causes COVID-19, inform methods to improve public health.

Three Wadsworth Center Researchers from the Laboratory of Viral Diseases, Chief Kirsten St. George, PhD; Research and Development Group Lead Daryl Lamson; and Research Scientist Lindsey Rickerman, sequenced SARS-CoV-2 from samples collected by partners who assisted with data analysis. 

Findings: More genetic diversity means more circulating virus and community transmission, and this approach, sequencing and analyzing degree of genetic diversity, can be applied to many infectious agents, making it a powerful tool for epidemiologists.

Partners

  • Syracuse University - Department of Public Health, Maxwell School of Citizenship and Public Affairs; Department of Biology; and the School of Information Studies
  • State University of New York, College of Environmental Science and Forestry
  • Upstate Medical University
  • New York State Department of Health, Wadsworth Center

Read the study

Genetic variability of SARS-CoV-2 in wastewater and associations with community transmission

Hill DT, Schulman R, Caldas IV, Dunham C, Zhu Y, Lamson D, Rickerman L, St George K, Ahmed-Braimah Y, Green H, Kmush BL, Middleton F, Larsen DA.

Science. 2026 May 14;392(6799):735-741. doi: 10.1126/science.aed6094. Epub 2026 May 14. PMID: 42133772.

 

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