Arthur H. Totten, PhD, F(CCM), D(ABMM)

Arthur H. Totten, PhD, F(CCM), D(ABMM)

Title
Deputy Chief, Laboratory of Viral Diseases
Director, General Virology Laboratory
Education
PhD, University of Alabama at Birmingham (UAB), Birmingham, AL (2018)
Postdoctoral Training: University of Alabama at Birmingham, Birmingham, AL (2018-2020)
CPEP Fellowship, National Institutes of Health (NIH), Bethesda, MD (2020-2022)

Dr. Totten is Deputy Chief of the Laboratory of Viral Diseases (LVD) and Director of the General Virology Laboratory (GVL) at the Wadsworth Center. The GVL is responsible for clinical, reference and surveillance testing for viruses and the investigation of outbreaks and emerging viral pathogens. Testing within the laboratory uses both viral isolation in cell culture and molecular detection techniques, including specialty methods for virus characterization.  

Dr. Totten has previously been a co-investigator or primary investigator on studies with the Centers for Disease Control and Prevention, as well as the National Institutes of Health. Prior work focused on virology, mycoplasmology, immunology and molecular microbiology. Within the GVL he oversees diagnostic and surveillance testing, and research projects within the scope of virology.

Dr. Totten has more than 10 years of experience with laboratory regulatory compliance,  quality assurance, and routine laboratory testing. He is a council member for the New York City Chapter of the American Society for Microbiology (ASM), as well as an active member of the CPEP Validation Sub-committee for ASM. Dr. Totten is passionate about scientific community outreach and engagement, and was awarded a Centers for the Integration of Research, Teaching and Learning (CIRTL) Program certification for didactic teaching in 2015. He has been involved in training undergraduate, graduate, medical and post-doctoral researchers and published numerous research manuscripts and book chapters. He is the recipient of the 2020 NIH Clinical Center CEO’s Award for clinical work during the COVID-19 pandemic, and the 2021 NIH Fellows Award for Research Excellence. His current research interests include the elucidation of novel viral pathogens, viral genomics, and the development of novel diagnostics for clinical implementation.

Professional Certifications:

Diplomat of the American Board of Medical Microbiology (D(ABMM), 2022)
Fellow of the Canadian College of Microbiology (F(CCM), 2024)

Select Publications
Totten AH, Adams AJ, Halas HK, Gebo JET, East AD, Lau AF. Comparison of Five Commercial Molecular Assays for Mycoplasma Testing of Cellular Therapy Products. J Clin Microbiol. 2023; Feb 22;61 (2): e0149822. DOI: 10.1128/jcm.01498-22.
Totten AH, Matlock AM, Bailin H, Revoir J, Siwy CM, Joyce M, Coffey P, Henderson DK, Palmore TN, Frank KM, McKeeby J. Experience with voluntary severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing of asymptomatic staff at the National Institutes of Health for one year. Infect Control Hosp Epidemiol. 2022; Nov;43 (11): 1661-1663. DOI: 10.1017/ice.2021.458
Totten AH, Youn JH, Roder A, Ghedin E, Palmore TN, Frank KM, Das S, Zelazny AM. Detection of SARS-CoV2 variants by Mesa Accula. J Clin Virol. 2021; Aug (141): 104901. DOI: 10.1016/j.jcv.2021.104901
Bernstock JD, Totten AH, Elkahloun AG, Johnson KR, Hurst AC, Goldman F, Groves AK, Mikhail FM, Atkinson TP. Recurrent microdeletions at chromosome 2p11.2 are associated with thymic hypoplasia and features resembling DiGeorge syndrome. J Allergy Clin Immunol. 2020; Jan;145 (1): 358-367.e2. DOI: 10.1016/j.jaci.2019.09.020
Leal SM Jr, Totten AH, Xiao L, Crabb DM, Ratliff A, Duffy LB, Fowler KB, Mixon E, Winchell JM, Diaz MH, Benitez AJ, Wolff BJ, Qin X, Tang YW, Gonzalez M, Selvarangan R, Hong T, Brooks E, Dallas S, Atkinson TP, Zheng X, Dien Bard J, Waites KB. Evaluation of Commercial Molecular Diagnostic Methods for Detection and Determination of Macrolide Resistance in Mycoplasma pneumoniae. J Clin Microbiol.. 2020; May 26;58 (6): e00242-20. DOI: 10.1128/JCM.00242-20
Totten AH, Leal SM Jr, Ratliff AE, Xiao L, Crabb DM, Waites KB. Evaluation of the ELITe InGenius PCR Platform for Detection of Mycoplasma pneumoniae. J Clin Microbiol. 2019; May 24;57 (6): e00287-19. DOI: 10.1128/JCM.00287-19