Michael J. Boucher, PhD
Print
BACK TO SENIOR STAFF

Michael J. Boucher, PhD

Title
Molecular Genetics of Fungal Pathogens
Education
PhD, Microbiology & Immunology, Stanford University (2019)
Postdoctoral Training, Department of Biochemistry & Biophysics, University of California, San Francisco
Phone Number
(518) 473-6033

Human fungal infections pose a massive public health burden yet remain severely understudied. Our lab develops and utilizes high-throughput genetic approaches to understand how fungal pathogens cause disease.

Select Publications
Boucher MJ, Banerjee S, Joshi MB, Wei AL, Nalley MJ, Huang MY, Lei S, Ciranni M, Condon A, Langen A, Goddard TD, Caradonna I, Goranov AI, Homer CM, Mortensen Y, Petnic S, Reilly MC, Xiong Y, Susa KJ, Pastore VP, Zaro BW, Madhani HD. Phenotypic landscape of an invasive fungal pathogen reveals its unique biology. Cell. 2025; 188 (15): 4003-4024.e24. DOI: 10.1016/j.cell.2025.05.017
Pubmed Web Address
Boucher MJ, Madhani HD. Convergent evolution of innate immune-modulating effectors in invasive fungal pathogens. Trends Microbiol. 2024; May;32 (5): 435-447. DOI: 10.1016/j.tim.2023.10.011
Pubmed Web Address
Huang MY, Joshi MB, Boucher MJ, Lee S, Loza LC, Gaylord EA, Doering TL, Madhani HD. Short homology-directed repair using optimized Cas9 in the pathogen Cryptococcus neoformans enables rapid gene deletion and tagging. Genetics. 2022; Jan 4;220 (1): iyab180. DOI: 10.1093/genetics/iyab180
Pubmed Web Address
Full publication listing