SCIRB Research Support | New York State Department of Health, Wadsworth Center

Funding Opportunities

To advance scientific knowledge and develop treatments and cures for spinal cord injury (SCI), the Extramural Grants Administration Program will issue requests for applications (RFAs) on behalf of the Spinal Cord Injury Research Board. Check this web site for updates or sign up for SCIRB eAlerts and indicate RFA as your area of interest.

Tips on managing graphics and file sizes submitted with your RFA or RFP are provided.

Available Funding Opportunities

RFA 20733 - New Investigator Award in Spinal Cord Injury Research (Round 1)

Funding Opportunities Pending Review

Recommended for Award

PART and IDEA (Round 8)

$5.03 million in the form of five (5) PART and four (4) IDEA awards were recommended.

Projects are three (3) years for PART awards and two (2) years for IDEA awards.

Contracting Entity	Funding Mechanism	Principal Investigator	Project Title	Recommended Funding
Albany Research Institute	IDEA	Jodi Brangaccio, DPT	taVNS-augmented H-reflex operant conditioning to reduce spasticity after SCI	$359,437
Bronx Veterans Medical Research Foundation	IDEA	Thomas Sutor, PhD	Transcutaneous spinal cord stimulation to enhance hemodynamics and performance during upright robotic-assisted stepping	$359,988
Research Foundation of City University of New York	PART	John Martin, PhD	Activity-dependent Trans-synaptic Neuron Degeneration Caudal to Cervical SCI	$951,821
Icahn School of Medicine at Mount Sinai	PART	Chung-Yinhg Tsai, PhD	Transcutaneous Spinal Cord Stimulation in Acute Inpatient Rehabvilitation to Enhance Recovery after Spinal Cord Injury - A Pilot Randomized Controlled Trial	$352,062
Icahn School of Medicine at Mount Sinai	IDEA	Hongyan Zou, MD, PhD	Modulating Injury Metaboloics to Enhance Spinal Cord Injury Recovery	$360,000
SUNY at Buffalo	PART	Hang Jin Jo, PhD	Neurophysiological Biomarkers for Repetitive Transcranial Magnetic Stimulation in SCI	$983,971
Research Foundation for State University of New York	PART	Blair Calancie, PhD	Developing a large animal model for repairing spinal nerves after cauda equina injury: An essential step towards a human clinical trial	$972,979
SUNY at Stony Brook	IDEA	Irene Solomon, PhD	Assessment of Repeated Task-Specific "fill-void" bladder therapy (BT) Sessions as a Novel Strategy to Restore Bladder Function in SCI	$357,740
SUNY at Binghamton	PART	Siyuan Rao, PhD	Multilaminar Intraspinal Recording to Reveal Early Circuit Reorganization After Spincal Cord Injury	$330,060
Total (9 awards)				$5,028,058

Predoctoral and Postdoctoral Fellowships (Fellowships) in Spinal Cord Injury Research (Round 7)

$723,800 in the form of three (3) Predoctoral and two (2) Postdoctoral Awards were recommended.

Contracting Entity	Funding Mechanism	Principal Investigator	Project Title	Recommended Award
The Trustees of Columbia University in the City of New York	Post Doctorate	Jason Carmel, MD, PhD & Maria Bandres, Post-Doctoral Fellow	Mechanisms of spinal activity for restoring skilled movement vs modulating reflexes in rats with SCI	$192,000
The Trustees of Columbia University in the City of New York	Pre Doctorate	Trina Arinzeh, PhD & Anna Kylat, Pre-Doctoral Fellow	A bifunctional fibrous scaffold for local delivery of a neuroregenerative peptide and guided axon growth for spinal cord repair	$116,000
Research Foundation of CUNY	Pre Doctorate	Ashiwel Undieh PhD & Chizurum Oluigbo Pre-Doctoral Fellow	Role of CDP-diacylglycerol signaling in motor function recovery following SCI	$119,800
Icahn School of Medicine at Mount Sinai	Post Doctorate	Hongyan Zou, PhD, MD & Chenye Shen Post-Doctoral Fellow	Investigate epigenetic memory of microglia in prolonging neuroinflammation in SCI	$192,000
Research foundation for the State University of New York	Pre Doctorate	Siyuan Rao PhD & Zuer Wu Pre-Doctoral Fellow	Soft Bioelectronics for Intraspinal Electrophysiology Monitoring and Localized Drug Infusion in Spinal Cord Injury Recovery	$104,000
Total (5 awards)				$723,800

Translational Research Projects in Spinal Cord Injury Round 7

$10.9M in the form of two (2) awards were recommended. Projects are five (5) years.

Contracting Entity	Principal Investigator	Project Title	Recommended Award
The Trustees of Columbia University in the City of New York	Jason Carmel, MD, PhD	Epidural versus transcutaneous cervical spinal cord stimulation to improve arm and hand function in chronic SCI	$5,777,634.84
The Trustees of Columbia University in the City of New York	Sunil Agriwal, PhD	Improving Seated Postural Control in People with Spinal Cord Injury with a Robotic Trunk Support Trainer (TruST)	$5,115,872.04

Projects to Accelerate Research Translation (PART) and Innovative, Developmental, or Exploratory Activities (IDEA) in Spinal Cord Injury (Round 7)

Organization	Principal Investigator	Project Title	Recommended Award
Research Foundation – SUNY	Hang Jin Jo Ph.D.	Neuromodulation to Improve Grasping Function After Spinal Cord Injury	$357,582
The Feinstein Institute for Medical Research	Ona Bloom, Ph.D.	Tolerability and preliminary efficacy of galantamine to treat metabolic syndrome in people with chronic spinal cord injury (SCI)	$340,57
Research Foundation – CUNY	John Martin, Ph.D.	Combined biomaterial scaffold - neuromodulation strategy for recovering function in preclinical model of rodent SCI	$990,000
Research Foundation – SUNY	Janet Paluh, Ph.D.	Molecular and Functional Outcomes of Combined Epidural Spinal Stimulation and Neuron Interneuron Excitatory Ribbons	$905,054
Bronx Veterans Medical Research Foundation	Jill Wecht, Ed.D.	AI-Guided Predictions of Blood Pressure Dysregulation using Perfusion Index as a Novel Biomarker in Persons with Spinal Cord Injury	$926,228
Bronx Veterans Medical Research Foundation	Carlos Toro, Ph.D.	Parenterally administered formulations of boldine to preserve function after SCI.	$345,000
Research Foundation – CUNY	Maria Knikou, Ph.D.	Cervical and Lumbosacral Transspinal Stimulation to Reconnect the Injured Human Spinal Cord	$922,983
Icahn School of Medicine at Mount Sinai	Hongyan Zou, Ph.D.	Transcriptional regulator of axon regeneration in SCI	$360,000
Sunnyview	Amy Teale, Ph.D.	Effectiveness of Sensorimotor Versus Motor-Only Training in Restoring Upper Limb Sensory and Motor Function for Patients with Spinal Cord Injury: A Comparative Study	$319,861
Total(9 awards)			$5,467,285

Predoctoral and Postdoctoral Fellowships in Spinal Cord Injury Research (Round 6)

Organization	Principal Investigator	Project Title	Recommended Award
Winifred Masterson Burke Medical Research Institute	Edmund Hollis, Ph.D.	Corticospinal dendritic dynamics during SCI rehabilitation	$192,000
Icahn School of Medicine at Mount Sinai	Hongyan Zou, MD, Ph.D.	The role of guidance molecule PlexinB1 in astrocytosis and wound compaction in SCI	$192,000
Syracuse University	Victor Duenas, Ph.D.	Development of a robotic leg stretching protocol to mitigate spasticity in people with SCI	$107,790
Total (3 awards)			$491,790

Translational Research Projects in Spinal Cord Injury (Round 6)

This RFA has been withdrawn.

Translational Research Projects in Spinal Cord Injury (Round 5) RFA.

Although no applications were recommended for this round, applicants are encouraged to resubmit their projects with revisions in response to the peer review critiques.

Projects to Accelerate Research Translation (PART) and Innovative, Developmental, or Exploratory Activities (IDEA) in Spinal Cord Injury (Round 6) RFA

Organization	Principal Investigator	Project Title	Recommended Award
Icahn School of Medicine at Mount Sinai	Thomas Bryce, MD	Biomarkers of Spinal Cord Injury Pain Evolution during Acute Rehabilitation (BioSPEAR)	$910,611
Winifred Masterson Burke Medical Research Institute	Edmund Hollis, PhD	Ephrin-mediated cortical motor circuit rewiring	$988,622
Icahn School of Medicine at Mount Sinai	Hongyan Jenny Zou, MD, PhD	Investigate glial communication in neural repair after SCI	$360,000
Winifred Masterson Burke Medical Research Institute	Vibhu Sahni, PhD	Structural plasticity of cortico-brainstem projections after spinal cord injury and their contribution to functional recovery	$360,000
Bronx Veterans Medical Research Foundation	Noam Harel, MD, PhD	Optimizing spinal cord associative plasticity to enhance response to hand training in cervical spinal cord injury	$946,581
University of Rochester	Bradford Berk, MD, PhD	PDE10A treatment for neuropathic pain after spinal cord injury	$359,294
Winifred Masterson Burke Medical Research Institute	Edmund Hollis, PhD	The contribution of Wallerian degeneration to neural tissue inflammation and axon regenera	$360,000
Bronx Veterans Medical Research Foundation	Weiping Qin, MD, PhD	Novel Targeting Nanotherapeutics for Functional Recovery after Acute SCI	$990,000
		Total (8 awards)	$5,275,108

Predoctoral and Postdoctoral Fellowships in Spinal Cord Injury Research (Round 5) RFA

Organization	Principal Investigator	Project Title	Recommended Award
Winifred Masterson Burke Medical Research Institute DBA Burke Neurological Institute	Alzahraa Amer, PhD, PT and Yutaka Yoshida, PhD	Restoration of Motor Function following Spinal Cord Injury via Optical Stimulation	$180,581
Columbia University	Windsor Ting, PhD and Jason B. Carmel, MD, PhD	Functional Dissection of the Rat Corticoreticular Pathway in Spinal Cord Injury	$190,000
The Research Foundation of CUNY - City College of New York	Jasmine Pathan, BA and John H. Martin, PhD	Activity and connectivity maintain premotor interneuron viability after SCI	$118,000
Rensselaer Polytechnic Institute	Adelle Hamilton, BS and Ryan J. Gilbert, PhD	Novel Poly(Pro-Gabapentin) Films to Provide Neuroprotection and Increase Neurite Extension	$122,400
Columbia University	Priya Kulkarni and Sunil K. Agrawal, PhD	Improving Trunk and Neck Coordination during Reaching Tasks with a Robotic Neck Brace in Individuals with Spinal Cord Injury	$116,000
Icahn School of Medicine at Mount Sinai	Nicholas Johnson, PhD and Ravi Iyengar, PhD	Multi-drug combination effects on physical therapy-enabled recovery after SCI	$191,978
Columbia University	Cahwin Ophaswongse, PhD and Sunil K. Agrawal, PhD	Improving Trunk Control while Seated on Wheelchairs in Individuals with Spinal Cord Injury using Robotics	$180,000
Cornell University	Catia Dombaxe, BS and Yadong Wang, PhD	Examine the effects Goldfish Extracellular Matrix (ECM) Hydrogel and Chondroitinase ABC (ChABC) in Injured Mice	$122,400
		Total (8 awards)	$1,221,359

Translational Research Projects (TRP) in Spinal Cord Injury (Round 4) RFA.

A total of $7.57 million in the form of two (2) TRP awards were recommended. These projects are five-year awards.

Organization	Principal Investigator	Project Title	Recommended Award
Columbia University	Sunil K. Agrawal, PhD	Improving Balance after Spinal Cord Injury Using a Robotic Upright Stand Trainer	$3,995,925
The Feinstein Institute for Medical Research	Chad E. Bouton, PhD	Constant and Cortically-Modulated Transcutaneous Spinal Cord Stimulation for the Treatment of Upper Extremity Impairment	$3,570,469
Total (2 awards)			$7,566,394

PART and IDEA in Spinal Cord Injury (Round 5) RFA.

A total of $5.75 million in the form of four (4) PART and five (5) IDEA awards were recommended. These projects are three- and two-year awards, respectively.

Organization	Principal Investigator	Funding Mechanism	Project Title	Recommended Award
Albany Research Institute, National Center for Adaptive Neurotechnologies	Disha Gupta, PhD	IDEA	Operant Conditioning of Somatosensory Evoked Potentials to Improve Motor Function after SCI	$356,538
Icahn School of Medicine at Mount Sinai	Leif A. Havton, MD, PhD	PART	Augmentation of Bladder Function by Transcutaneous Spinal Cord Stimulation after Conus Medullaris Injury in Primates	$995,000
Sloan Kettering Institute for Cancer Research	Dimitar B. Nikolov, PhD	IDEA	Promoting Neuronal Regeneration by Targeting the Alpha Secretase Cleavage of p75 with Monoclonal Antibodies	$360,000
Stony Brook University	Irene C. Solomon, PhD	PART	Therapeutic Intermittent Hypoxia to Reduce Detrusor Overactivity and Symptom Severity in Chronic Incomplete SCI: Translation and Mechanisms	$986,610
The City College of New York	Ashiwel S. Undieh, PhD	IDEA	Nucleolipid Signaling for Spinal Cord Regeneration	$360,000
The City College of New York	John Martin, PhD	PART	Leveraging LTP to Promote CST Axon Sprouting in the Spinal Cord	$982,800
Winifred Masterson Burke Medical Research Institute DBA Burke Neurological Institute	Edmund R. Hollis, PhD	IDEA	Role of SPARC in Pathological Wound Healing after Spinal Cord Injury	$360,000
Winifred Masterson Burke Medical Research Institute DBA Burke Neurological Institute	Edmund R. Hollis, PhD	PART	Enhancing Nerve Transfer Surgery to Restore Hand and Arm Function in Chronic Tetraplegia	$990,000
Winifred Masterson Burke Medical Research Institute DBA Brain and Mind Research Institute	Vibhu V.Sahni, PhD	IDEA	Mechanisms Controlling Early and Segmentally Distinct Loss of Long Distance Corticospinal Axon Regenerative Ability	$360,000
Total (9 awards)				$5,750,948

TRP in Spinal Cord Injury (Round 3) RFA.

Although no applications were recommended for this round, applicants are encouraged to resubmit their projects with revisions in response to the peer review critiques.

PART and IDEA in Spinal Cord Injury (Round 4) RFA.

A total of $3.8 million in the form of one (1) PART and eight (8) IDEA awards were recommended. These projects are three- and two-year awards, respectively.

Organization	Principal Investigator	Funding Mechanism	Project Title	Recommended Award
Cornell University	Yadong Wang, PhD	IDEA	Investigating Regenerative Goldfish Extracellular Matrix in Mammalian SCI	$360,000
Icahn School of Medicine at Mount Sinai	Mar Cortes, MD	IDEA	Long Term Effects of rTMS in Chronic Neuropathic Pain in People with SCI	$357,170
Research Foundation for SUNY Stony Brook	Michelino Puopolo, PhD	IDEA	Targeting CaV3.2 Calcium Channel to Treat Chronic Neuropathic Pain Following SCI	$360,000
Research Foundation for SUNY Stony Brook	Irene C. Solomon, PhD	IDEA	Neuroprotective Strategies to Minimize SCI Tissue Damage and Improve Bladder and Respiratory Function	$357,782
Research Foundation for SUNY, University at Albany	Ben G. Szaro, PhD	IDEA	Elemental Analysis of a Gene Network Implicated in CNS Axon Regeneration	$351,031
The Research Foundation of CUNY obo College of Staten Island	Maria Knikou, PT, PhD	IDEA	Function of Spinal Locomotor Centers During Transspinal Stimulation After SCI	$359,004
The Trustees of Columbia University in the City of New York	Sunil K. Agrawal, PhD	IDEA	Wheelchair Robot for Active Postural Support (WRAPS) of People with Spinal Cord Injury	$346,220
Winifred Masterson Burke Medical Research Institute	Yutaka Yoshida, PhD	IDEA	Modulation of Presynaptic Partners of Corticospinal Neurons to Improve Motor Recovery After Spinal Cord Injury	$360,000
Winifred Masterson Burke Medical Research Institute	Yutaka Yoshida, PhD	PART	Novel Combinatorial Approach to Improve Motor Recovery After Spinal Cord Injury	$990,000
Total (9 awards)				$3,841,207

Individual Predoctoral and Postdoctoral Fellowships in Spinal Cord Injury Research (Round 4) RFA.

A total of $1.16 million in the form of three (3) predoctoral and four (4) post-doctoral awards were recommended. Projects are three-year awards.

Organization	Investigators	Funding Mechanism	Project Title	Recommended Award
Burke Medical Research Institute	Jason B. Carmel, MD, PhD and Bushra Yasin, MD, PhD	Postdoc	Paired Brain and Spinal Cord Stimulation to Augment Motor Responses in People with Cervical Myelopathy	$192,366
Columbia University	Sunil K. Agrawal, PhD and Tatiana D. Luna, MS	Predoc	Improving Upper Body Trunk Control in Spinal Cord Injury Patients Through Robotic Rehabilitation Training	$135,600
Icahn School of Medicine at Mount Sinai	Ann M. Spungen, EdD and Chung-Ying Tsai, PhD	Postdoc	The Effects of Incorporated Exoskeletal-Assisted Walking in SCI Acute Inpatient Rehabilitation	$189,476
New York University School of Medicine	Dan R. Littman, MD, PhD and Hyeon Kyu (Alice) Kwon, BS	Predoc	Enteric Glial Cells Cause Gastrointestinal Complications Post Spinal Cord Injury	$135,600
Regenerative Research Foundation	Sally Temple, PhD and Elizabeth Fisher, PhD	Postdoc	Modulation of Inflammation Following SCI Using Plasmid IL-10 Microbeads	$184,686
Rensselaer Polytechnic Institute	Ryan J. Gilbert, PhD and Jessica Funnell, BS	Predoc	Neuroprotective Curcumin-Releasing Hydrogel for Treatment of Acute Spinal Injury	$135,600
University of Rochester Medical Center	Bradford C. Berk, MD, PhD and Chia Hsu, PhD	Postdoc	The Role of Phosphodiesterase 10A in Inflammation After Spinal Cord Injury	$189,366
Total (7 awards)				$1,162,694

PART and IDEA in Spinal Cord Injury (Round 3) RFA.

A total of $4.1 million in the form of three (3) PART and four (4) IDEA awards were recommended. These projects are three- and two-year awards, respectively.

Organization	Principal Investigator	Funding Mechanism	Project Title	Recommended Award
Bronx Veterans Medical Research Foundation	William A. Bauman, MD	PART	Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI	$826,939
Icahn School of Medicine at Mount Sinai	Ravi Iyengar, PhD	IDEA	Systems Therapeutics for Spinal Cord Injury	$342,914
Icahn School of Medicine at Mount Sinai	David F. Putrino, PT, PhD	IDEA	Virtual Reality to Reduce Pain in the Upper Extremities After Spinal Cord Injury	$357,639
University of Rochester	Gail V.W. Johnson, PhD	IDEA	Transglutaminase 2 as a Therapeutic Target to Facilitate Recovery After Spinal Cord Injury	$360,000
Winifred Masterson Burke Medical Research Institute	Edmund R. Hollis, PhD	PART	Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury	$963,000
Winifred Masterson Burke Medical Research Institute	Botir T. Sagdullaev, PhD	IDEA	Blood Flow Control and its Impairment in Spinal Cord Injury	$357,566
Winifred Masterson Burke Medical Research Institute	Jian Zhong, PhD	PART	Repetitive Transcranial Magnetic Stimulation as a means to Promote CST Axon Regeneration	$990,000
Total (7 awards)				$4,198,058

Individual Predoctoral and Postdoctoral Fellowships in Spinal Cord Injury Research (Round 3) RFA.

A total of $1.2 million in the form of two (2) predoctoral and five (5) post-doctoral awards were recommended. Projects are three-year awards.

Organization	Investigators	Funding Mechanism	Project Title	Recommended Award
Rensselaer Polytechnic Institute	Ryan J. Gilbert, PhD, Devan Puhl	Predoc	Delivery of Neurotrophin-3 mRNA by Electrospun Fibers to Promote Axonal Growth	$135,600
Research Foundation of CUNY obo The City College of New York	John Martin, PhD, Lillian Yang, PhD	Postdoc	Harnessing Activity-Dependent Competition to Repair the Corticospinal Motor System After Cervical Spinal Cord Injury	$184,734
Stony Brook University	Prithvi K. Shah, PhD, Pawan Sharma	Predoc	Activity-dependent Closed-loop Neuromodulation of the Cervical Spinal Cord for the Recovery of Skilled Upper Limb Function After a Spinal Cord Injury	$117,570
Winifred Masterson Burke Medical Research Institute	Jason B. Carmel, MD, PhD, Qi Yang, PhD	Postdoc	Combined Therapy of Forelimb Area Motor Cortex and Spinal Cord Epidural Stimulation to Improve Hand Function After Spinal Cord Injury and Identifying the Responsible Pathway	$186,426
Winifred Masterson Burke Medical Research Institute	Caitlin E. Hill, PhD, Carolin Ruven, PhD	Postdoc	Role of Ubiquitinated Proteins in Dystrophic Axonal Endings Following Spinal Cord Injury	$186,426
Winifred Masterson Burke Medical Research Institute	Edmund R. Hollis, PhD, Hisham Mohammed, PhD	Postdoc	The Role of Intracortical Circuits in Motor Recovery from Spinal Cord Injury	$175,926
Winifred Masterson Burke Medical Research Institute	Jian Zhong, PhD, Ning Xia, MD, PhD	Postdoc	Generation and Validation of a Transgenic Chainamplifying Tracer (TCAT) Mouse Line	$172,926
Total (7 awards)				$1,159,608

PART and IDEA in Spinal Cord Injury (Round 2) RFA.

A total of $6.5 million in the form of three (3) PART and eleven (11) IDEA awards were recommended. These projects are three- and two-year awards, respectively.

Organization	Investigators	Funding Mechanism	Project Title	Recommended Award
Bronx Veterans Medical Research Foundation Sub-applicant- Icahn School of Medicine at Mount Sinai	Christopher Cardozo, MD, Dongming Cai, MD, PhD, Bin Zhang, PhD	IDEA	Role of Synaptojanin 1 in Functional Recovery after Spinal Cord Injury	$344,624
Bronx Veterans Medical Research Foundation	Jill Wecht, EdD	IDEA	Dose Effect of Norepinephrine Precursor (Droxidopa) on Blood Pressure and Cerebral Blood Flow Velocity in Hypotensive Individuals with Spinal Cord Injury	$344,887
Feinstein Institute for Medical Research Sub-applicant- Bronx Veterans Medical Research Foundation	Ona Bloom, PhD, Ann Spungen, EdD	IDEA	Impact of Walking on the Immune System of Persons with Chronic Spinal Cord Injury	$222,870
Icahn School of Medicine at Mount Sinai	Hongyan Jenny Zou, MD, PhD	IDEA	Enhancing Axon Regenerative Capacity Through Epigenetic Regulation of DNA Methylation Dynamics	$360,000
Regenerative Research Foundation Sub-applicant- Marine Biological Laboratory	David Butler, PhD, Jennifer Morgan, PhD	IDEA	Developing Intracellular Antibodies Against Alpha-Synuclein as Potential Therapeutics in Spinal Cord Injury and Disease	$311,921
Regenerative Research Foundation Sub-applicant- The Children's Hospital Corporation	Sally Temple, PhD, Larry Benowitz, PhD	IDEA	The Role of Zinc in Axon Regeneration Following Spinal Cord Injury	$335,000
Research Foundation of CUNY obo City College of New York Sub-applicant- Columbia University	John Martin, PhD, Sunil Agrawal, PhD	IDEA	Robotic Rehabilitation to Promote Recovery of Forelimb Function after Cervical SCI in Rats	$332,738
Research Foundation of CUNY obo College of Staten Island Sub-applicant- Bronx Veterans Medical Research Foundation	Maria Knikou, PT, PhD, Noam Harel, MD, PhD	PART	Activity-Dependent Transspinal Stimulation for Recovery of Walking Ability after SCI	$898,595
Research Foundation for SUNY - SUNY Polytechnic Institute Sub-applicant- The Methodist Hospital Research Institute	Janet Paluh, PhD, Philip Horner, PhD	PART	Healing the Contusion-Injured Spinal Cord Microenvironment with Nanotechnology- and Stem Cell- Assisted Modulation	$970,404
University of Rochester	Mark Noble, PhD	PART	Acute Treatment with 4-aminopyridine Promotes Extensive Recovery from Traumatic SCI	$990,000
Winifred Masterson Burke Medical Research Institute	Jason Carmel, MD, PhD	IDEA	Combining 4-AP with Motor Training to Promote Forelimb Motor Recovery in Rats with Pyramidal Tract Injury	$359,241
Winifred Masterson Burke Medical Research Institute	John Cave, PhD	IDEA	Molecular Mechanisms Regulating Cell Adhesion in Reactive Astrocytes and Glial Scar Formation Following Spinal Cord Injury	$360,000
Winifred Masterson Burke Medical Research Institute Sub-applicant- University of Michigan	Edmund Hollis, PhD, Roman Giger, PhD	IDEA	Immune-mediated Nervous System Repair	$360,000
Winifred Masterson Burke Medical Research Institute	Jian Zhong, PhD	IDEA	Investigating Axonal mRNA Translation in CST Axon Sprouting and Regeneration	$360,000
Total (14 awards)				$6,550,280

Translational Research Projects (TRP) in Spinal Cord Injury (Round 2) RFA .

A total of $2.8 million in the form of two (2) TRP awards were recommended. Both projects are four-year awards.

Organization	Investigators	Project Title	Recommended Award
Health Research, Inc. Sub-applicant- Medical University of South Carolina	Johnathan Wolpaw, MD, Gerwin Schalk, PhD	A Spinal Reflex Operant Conditioning System Suitable for Clinical Translation	$1,623,620
University of Rochester	Mark Noble, PhD, Christoph Proschel, PhD	Pharmacological Treatment of Acute Spinal Cord Injury	$1,203,455
Total (2 awards)			$2,827,075

Individual Predoctoral and Postdoctoral Fellowships in Spinal Cord Injury Research (Round 2) RFA.

A total of $1.5 million in the form of two (2) predoctoral and seven (7) post-doctoral awards were recommended. These projects are three-year awards.

Organization	Investigators	Funding Mechanism	Project Title	Recommended Award
Bronx Veterans Medical Research Foundation, Inc.	Noam Harel, MD, PhD, Yu-Kuang Wu, PT, PhD	Postdoc	EMG Triggered Closed-Loop Stimulation for Spinal Cord Injury Individuals	$187,440
Columbia University	Sunil K. Agrawal, PhD, Dario Martelli, PhD	Postdoc	Improving Locomotor Function After Spinal Cord Injury with a Perturbation-Based Balance Training	$193,482
Cornell University	Chris B. Schaffer, PhD, Yu-Ting Chen, PhD	Predoc	In Vivo Three-Photon Excited Fluorescence Imaging of Spinal Cord Neural Activity in Awake, Locomoting Mice after Spinal Cord Injury	$135,600
Feinstein Institute for Medical Research	Ona Bloom, PhD, Nawshin Kutub, PhD	Postdoc	Biomarkers in Adult and Pediatric Traumatic Spinal Cord Injury	$168,414
Icahn School of Medicine at Mount Sinai	Hongyan Zou, PhD, MD, Shalaka D. Wahane, PhD	Postdoc	Epigenetic Modulation of Immune Response to Enhance Neuroprotection in Spinal Cord Injury	$176,550
Rensselaer Polytechnic Institute	Ryan J. Gilbert, PhD, Anthony D'Amato, PhD	Predoc	Estrogen Based Biomaterials Promote Astrocytic Growth Factor Production and Provide Neuroprotection Against Glutamate Excitotoxicity	$135,600
University of Rochester	Christoph Proschel, PhD, Jennifer Stripay, PhD	Postdoc	Novel Pharmacological Approach to Promoting Myelin Preservation, Neuronal Regeneration and Preventing Muscle Atrophy Following SCI	$176,454
Winifred Masterson Burke Medical Research Institute	Caitlin E. Hill, PhD, Ying Dai, PhD	Postdoc	Improving Axonal Growth Through Schwann Cell Transplant by the Activation of Integrin Following SCI	$174,090
Winifred Masterson Burke Medical Research Institute	Edmund R. Hollis, PhD, Yue Li, PhD	Postdoc	Motor Learning Mechanisms During Rehabilitation from Spinal Cord Injury	$168,414
Total (9 awards)				$1,516,044

Institutional Support for Spinal Cord Injury Research (Round 6) Solicitation of Interest

Twenty (20) eligible organizations received letters of support for the expansion of spinal cord injury research within their organizations. These projects are five-year awards.

PART and IDEA in Spinal Cord Injury (Round 1) RFA.

A total of $6.2 million in the form of four (4) PART and seven (7) IDEA awards were recommended. These projects are three- and two- year awards, respectively.

Organization	Investigators	Funding Mechanism	Project Title	Recommended Award
Bronx Veterans Medical Research Foundation	Hesham Tawfeek, MD	IDEA	Role of T Cells in Bone Loss After Spinal Cord Injury	$356,999
Columbia University	Ulrich Hengst, PhD	IDEA	Pumilio 1 and 2 Control Axon Regrowth by Shaping the Axonal Transcriptome	$360,000
Cornell University	Chris B. Schaffer, PhD	IDEA	Imaging Neural Activity in the Spinal Cord of Awake Mice After Spinal Cord Injury	$350,876
Research Corporation of Long Island, Inc. Sub-applicant- Houston Methodist Research Institute	Victor L. Arvanian, PhD, DSci, Philip J. Homer, PhD	PART	Neuroplasticity Integrting Human Induced Neuralized Pluripotent Stem Cells (NiPSCs) in SCI Animals	$935,867
Research Foundation for SUNY Stony Brook	Sue Ann Sisto, PhD, Victor Arvanian, PhD	PART	Effects of Spinal Electromagnetic Stimulation and Locomotor Training on Motor Recovery and Walking in Incomplete SCI	$989,199
Research Foundation for SUNY Stony Brook	Irene C. Solomon, PhD, William F. Collins, PhD	IDEA	Therapeutic Potential of Mild to Moderate AIH on LUT and Respiratory Function in SCI	$355,111
Research Foundation for SUNY, University at Albany	Ben G. Szaro, PhD	IDEA	Functional Analysis of Genes Implicated in Successful CNS Axon Regeneration	$359,738
Research Foundation of CUNY obo College of Staten Island	Maria Knikou, PT, PhD	PART	Transspinal-Transcortical Paired Stimulation for Neuroplasticity and Recovery After SCI	$947,004
Weill Medical College of Cornell University Sub-applicant- Winifred Masterson Burke Medical Research Institute	Anthony Sauve, PhD, Brett C. Langley, PhD	PART	NAD-Augmenting Agents to Enhance Neural Survival and Function Following Spinal Cord Injury	$890,241
Winifred Masterson Burke Medical Research Institute Sub-applicant- Massachusetts Institute of Technology	Dylan J. Edwards, PhD, PT	IDEA	Improving Hand Function in Chronic SCI with Combined Robot Training and Transcranial Direct Current Stimulation	$359,000
Winifred Masterson Burke Medical Research Institute	Jian Zhong, PhD	IDEA	Visualizing New Synapses and Their Activity in the Injured Spinal Cord	$360,000
Total (11 awards)				$6,264,035

TRP in Spinal Cord Injury (Round 1) RFA

A total of $8,771,302 was recommended for two (2) TRP awards. These projects are five-year awards.

Organization	Investigators	Project Title	Recommended Award
Columbia University Sub-applicant- University of Louisville Research Foundation	Sunil K. Agrawal, PhD, Susan J. Harkema, PhD	Tethered Pelvic Assist Device (TPAD) and Epidural Stimulation for Recovery of Standing in SCI	$5,033,354
RFCUNY obo The City College of NY/CUNY School of Medicine Sub-applicants- Winifred Masterson Burke Medical Research Institute, Bronx Veterans Medical Research Foundation	John Martin, PhD, Jason B. Carmel, MD, PhD, Noam Y. Harel, MD, PhD	Combined Motor Cortex and Spinal Cord Stimulation to Promote Arm and Hand Function After Chronic Cervical Spinal Cord Injury	$3,737,948
Total (2 awards)			$8,771,302

Individual Predoctoral and Postdoctoral Fellowships in Spinal Cord Injury Research RFA

A total of $822,541 in the form of four (4) predoctoral and two (2) post-doctoral awards were recommended. These projects are three-year awards. *Denotes that the awardee declined funding due to prior acceptance of National Institutes of Health funding.

Organization	Investigators	Funding Mechanism	Project Title	Recommended Award
Rensselaer Polytechnic Institute	Ryan Gilbert, PhD, Christopher Johnson, DL, BS	Predoc	Magnetic Alignment of Electrospun Fibers for Treatment of Acute Spinal Cord Contusive Injury	$135,600
Research Foundation for SUNY, University at Albany	Ben Szaro, PhD, Rupa Choudhary, MS	Predoc	Intracellular Modulations of Cytokine Signaling Leading to Successful CNS Axon Regeneration in a Vertebrate Model	$85,585
The Research Foundation of CUNY obo City College of New York	John Martin, PhD, Alzahraa Amer, MS	Predoc	Modulating Spinal Cord Neural Activity to Promote Recovery of Motor Function After SCI	$135,600
*The Trustees of Columbia University in the City of New York	Ulrich Hengst, PhD, Jose C. Martínez	Predoc	Control of the Transcriptome in Regenerating Axons Through mRNA Degradation	$127,500
Winifred Masterson Burke Medical Research Institute	Jason Carmel, MD, PhD, Hongguen Park, PhD	Postdoc	Dissecting and Strengthening Corticospinal Connections After Spinal Cord Injury Using Advanced Neuroscience Methods	$172,902
Winifred Masterson Burke Medical Research Institute	Jian Zhong, PhD, Mariel Voutounou, PhD	Postdoc	Promoting Intrinsic Growth Competency of Injured Neurons Using Genetic and Small Molecule Approaches	$165,354
			Total (6 awards)	$822,541

Collaborations to Accelerate Research Translation (CART) and IDEA in Spinal Cord Injury Research RFA

A total of $5.7 million in the form of three (3) CART and six (6) IDEA awards were recommended. These projects are three- and two-year awards, respectively.

Organization	Investigators	Funding Mechanism	Project Title	Recommended Award
Albert Einstein College of Medicine, Yeshiva University	David Sharp, PhD, Kelvin P. Davies, PhD, Sylvia O. Suadicani, PhD	CART	Harnessing Microtubules to Enhance Urological Function After Spinal Cord Injury	$1,197,182
Burke Medical Research Institute	Dianna Willis, PhD	IDEA	Alterations in Extracellular Vesicle Communication as a Cause of NMJ Dysfunction After SCI	$448,978
Burke Medical Research Institute	Jason Carmel, MD, PhD	IDEA	Delayed Versus Immediate Motor Training Following Brain Stimulation to Enhance Recovery in Rats with Chronic Corticospinal Tract Injury	$450,419
CUNY City College of New York	John Martin, PhD	CART	Repairing the Damaged Corticospinal Tract after Cervical Spinal Cord Injury	$990,000
Health Research Incorporated, Wadsworth Center	Jonathan Carp, PhD	IDEA	Role of Abnormal Urethral Sphincter Motoneuron Properties in Urinary Tract Dysfunction After Spinal Cord Injury	$442,373
Icahn School of Medicine at Mount Sinai	Hongyan Zou, MD, PhD	IDEA	The Role of HDAC3 in the Epigenetic Regulation of Functional Polarization of Microglia and Macrophages After Spinal Cord Injury	$360,000
Icahn School of Medicine at Mount Sinai	Noam Harel, MD, PhD	IDEA	Augmenting Hand Muscle Control in Cervical SCI through Paired Cortical and Cervical Stimulation	$391,353
Regenerative Research Foundation	Sally Temple, PhD	CART	Sustained Delivery of IL10 and SHH to Promote Spinal Cord Regeneration After Injury	$1,097,684
SUNY Downstate Medical Center	Joseph Francis, PhD	IDEA	24/7 Use of Fully Integrated Bi-Directional Autonomous Brain Machine Interface in Non-Human-Primates	$341,559
			Total (9 awards)	$5,719,548