A culmination of work in Lyme arthritis in patients and in animal models, the review highlights the paradigm that infectious agents may trigger immune dysregulation and autoimmunity, leading to persistent post-infectious sequelae.
Lyme arthritis: linking infection, inflammation and autoimmunity.
Lochhead RB, Strle K, Arvikar SL, Weis JJ, Steere AC. Nat Rev Rheumatol. 2021 Aug;17(8):449-461. doi: 10.1038/s41584-021-00648-5. Epub 2021 Jul 5. PMID: 34226730 Review.
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