The New York State Newborn Screening Program housed at the Wadsworth Center was the first program in the U.S. to implement screening for sickle cell disease in 1975. Sickle cell disease is an inherited blood disorder affecting hemoglobin, the major protein that carries oxygen in red blood cells. The abnormal hemoglobin causes sickle-shaped red blood cells that can break down prematurely and/or block blood flow, leading to anemia, pain, infections, and other severe complications. Sickle cell disease affects more than 100,000 people in the U.S.

Approximately half of all cases of reported infertility in the United States involve malefactor, which is commonly diagnosed via standardized analysis of semen quality parameters that include sperm concentration, motility, and morphology.  

September is designated as Public Health Laboratory Appreciation Month. Wadsworth Center proudly joined the Association of Public Health Laboratories and colleagues nationwide in honoring the vital role these laboratories—and every individual within them—play in protecting public health. 

Read the New York State Department of Health Press Release.

Read the Association of Public Health Laboratories' Blog post spotlighting Wadsworth Center scientist Jean Rock.

In August, Brooke Clemons of the Parasitology Laboratory and Kiran Mall of the Protein Expression and Biochemistry Core Laboratories graduated from the Association of Public Health Laboratories (APHL) Emerging Leader Program (ELP), Cohort 18.  They were selected as two of 25 participants nationwide for this yearlong program designed to cultivate leadership skills among laboratory professionals from state and local public health laboratories.  

The Wadsworth Center Biodefense Laboratory has been awarded $125,000 to develop, optimize, and validate threat-agnostic sequencing workflows for the rapid detection of pathogens in respiratory and other specimens. This project represents a critical step in strengthening New York State’s laboratory readiness and capacity to respond to infectious disease threats.  The initiative will integrate metagenomic and targeted sequencing methods with the Johns Hopkins University Applied Physics Laboratory Basestack software, including its TaxTriage module. 

Minneapolis, MN | September 7-9, 2025 – Dr. Norma Tavakoli, PhD, of the Wadsworth Center was a featured speaker at the Congenital Cytomegalovirus (cCMV) Public Health and Policy Conference, hosted by the University of Minnesota.  Her presentation, “A Pilot Study in New York State to Screen Newborns for Congenital Cytomegalovirus,” highlighted groundbreaking work conducted by the New York State Newborn Screening Program.  

The New York State Newborn Screening Program at the Wadsworth Center has become the first program in the United States to implement universal newborn screening for Metachromatic Leukodystrophy (MLD), a devastating but now treatable lysosomal storage disorder.  MLD is caused by low or absent activity of the arylsulfatase A (ARSA) enzyme, leading to toxic accumulation of sulfatides and progressive damage to the nervous system.

Dr. Rajendra Agrawal of the Wadsworth Center was invited to speak at the Ribo25 Symposium (September 18–19, 2025) at the Medical Research Council’s Laboratory of Molecular Biology (MRC-LMB), marking 25 years since the atomic structure of a bacterial ribosome subunit was solved – a discovery recognized with the 2009 Nobel Prize in Chemistry.  Dr. Agrawal’s presentation, “The mammalian mitochondrial ribosomes: From first glimpses to current insights,” highlighted the Wadsworth Center’s pioneering work in mammalian (human) mitochondrial ribosome research.