Recent advances have transformed neuroscience research. Wadsworth scientists and engineers are augmenting and exploiting these advances in many different areas. For example, several investigators study the genetic, anatomical, physiological, and immunological bases of neurodevelopmental, neurodegenerative, environmental, and traumatic disorders. Furthermore, the recent realization that activity-dependent plasticity occurs continually throughout the CNS and throughout life, and that new technology can support complex real-time adaptive interactions with the CNS to induce and guide this plasticity, enables others to develop powerful new research tools and therapeutic methods that can restore useful function to people disabled by injury or disease. These investigators are developing new methods for interacting with the CNS so as to induce plasticity and improve impaired functions. They place strong emphasis on translating basic science advances achieved in the laboratory into clinical studies in humans and eventually into clinical practice. This translational work is concentrated in the new Wadsworth-based National Center for Adaptive Neurotechnologies, which is supported by a P41 grant from the National Institute of Biomedical Imaging and Bioengineering.
Neuroscience & Neurotechnology
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Neuroscience & Neurotechnology
Associated Researchers
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Xiang Yang Chen, Ph.D.
- National Center for Adaptive Neurotechnologies
We elucidate in animal models the complex patterns of brain and spinal cord plasticity that underlie motor skills, and explore how we can enhance CNS plasticity and guide it to promote functional recovery in humans after injury or disease.
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David A. Lawrence, Ph.D.
- Neuroimmunology and Immunotoxicology
We study the immunological aspect of the system biology effects from genetic susceptibilities and environmental stress defined as the exposome on autoimmune diseases, immune deficiencies, and neurodegenerative and neurobehavioral illnesses.
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Gerwin Schalk, Ph.D.
- National Center for Adaptive Neurotechnologies
We have developed methods for characterizing complex brain signal processes detected by recordings directly from the surface of the brain. We are using them to acquire new neuroscientific insights and to develop new diagnostic methods for neurosurgery.
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Jonathan R. Wolpaw, M.D.
- Director of the National Center for Adaptive Neurotechnologies
We have designed protocols for changing specific pathways in the central nervous system. With these protocols, we explore mechanisms of learning and memory and develop new therapies to restore function to people with spinal cord injury or other disorders.