My lab investigates how the gut microbiome and host co-metabolism of diet and environmental pollutants shape cancer risk and early-life disease. We use untargeted metabolomics, multi-omics integration, microbial culture systems, organoids, and preclinical models to map how bacteria and the host generate bioactive metabolites that influence toxicity, inflammation, and tumor progression.
A major focus is understanding subsite-specific microbial–metabolite interactions in colorectal cancer and their links to liver metastasis and tumor heterogeneity. We also study how pollutant- and diet-driven metabolic variation in human populations contributes to cancer susceptibility, including risks in childhood cancer. Our group develops advanced metabolomics technologies and computational tools to identify novel conjugated metabolites and biomarker discovery. Ultimately, we aim to uncover microbial-metabolite signatures that enable early detection and guide microbiome-informed cancer prevention and therapy.
Join Us!
Our lab is growing, and we are actively recruiting at all levels. We have several exciting projects ready to advance, and we always welcome innovative ideas from new team members. If you’re interested in joining our team or discussing potential opportunities, please reach out—we’d love to hear from you.
APHL–CDC Fellowship Applicants
Our lab is an approved host site for the APHL–CDC Fellowship. If you would like to work with us through this fellowship, please contact us—we’d be happy to discuss potential projects and how your interests fit within our program.