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The ability to rapidly detect and respond to the intentional release of pathogens and toxins is vital in protecting the health and well-being of New Yorkers. The intentional release of Bacillus anthracis through the US Postal Service in 2001…

Tuberculosis is the number one killer among infectious diseases and is responsible for 2 to 3 million deaths per year around the world. The recent emergence of multi- and extensively drug resistant strains (MDR and XDR, respectively) represents a…

As Director of the Division of Laboratory Operations, Dr. Glaser provides overall programmatic, staffing, and budgetary guidance and direction to all programs within the Division, ensuring the best possible support services to all the Center's…

Mycobacteria are a diverse family of bacteria that includes the pathogens that cause the specific diseases tuberculosis, Hansen’s disease (leprosy) and Buruli Ulcer. Other environmental mycobacteria cause opportunistic infections in soft tissues,…

We use laser microsurgery and sophisticated imaging techniques (light- and electron microscopy) to study molecular mechanisms responsible for faithful segregation of chromosomes during mitosis (cell division). The mitotic apparatus, a.k.a. the…

My research and teaching interests lie in the field of Environmental Health. Active research programs include:Effects of particulate matter on daily morbidity and mortality due to cardiovascular and pulmonary diseases in large cities.Chemical…

The Tissue Resources Program oversees all tissue banking activities and services provided in New York State, from donor solicitation to clinical use. Public Health Law Article 43-B, enacted in 1990, established the Commissioner's authority…

A long-term research focus has been the generation of immunologic memory. The T cells which are responsible for immunologic memory differ, both phenotypically and functionally, from naive T cells. Memory T cells play a central role in all aspects of…

My laboratory develops improved methods of detecting, identifying and characterizing parasites that infect humans, as well as investigating pathogenicity and sources of infection.  Because culture is not possible as a means of enhancing…

Dr. Mantis’ research focuses on host-pathogen interactions and the development of vaccines for biodefense and emerging infectious diseases (BDEID). His primary interest is in the role of antibodies in conferring immunity to airborne, foodborne and…

Our laboratory studies the molecular biology of coronaviruses, a family of enveloped RNA viruses that cause respiratory, enteric, and neurologic diseases in mammalian and avian hosts. In humans, four endemic coronaviruses are responsible for highly…

The focus of the McDonough Laboratory is gene regulation in the context of bacterial pathogenesis, or the means by which bacteria cause disease. The team is primarily interested in two well known pathogens: Mycobacterium tuberculosis, the…

Our laboratory studies how bacteria regulate their gene expression. We are particularly interested in transcriptional regulation in the non-pathogenic model organism Escherichia coli, and in pathogenic strains of Salmonella and Yersinia. We also…

The Newborn Screening Program at Wadsworth Center tests for over 40 genetic disorders in newborns. Infants who have one of several rare genetic disorders and infants who have been exposed to HIV are identified promptly; with medical treatment…

Copy number variants (CNVs) are frequent and widespread in the human genome and alter dosage of genes important in conditions ranging from HIV susceptibility to autism spectrum disorders (ASDs). Thus, CNVs are potential diagnostic tools for clinical…

Dr. St. George is Director of Virology and Chief of the Laboratory of Viral Diseases (LVD) at the Wadsworth Center, and a Clinical Professor in the Department of Biomedical Sciences, College of Integrated Health Sciences, University at Albany.…

We are interested in understanding the structural basis of macromolecular assemblies in their functional context. The lab utilizes structural imaging methods, in combination with molecular and biochemical approaches, to study the structure and…

Genome replication is a fundamentally important process in all cells and viruses. Mistakes made during replication cause mutations as well as large scale genome rearrangements, which can ultimately cause antibiotic resistance in bacteria as well as…

Dr. Parsons has been investigating how different trace elements can affect human health for more than 40 years. The goal of this research is to provide better insights into what is now called the “exposome”. The CDC, defines the exposome as “the…

Mosquito-borne arboviruses (arthropod-borne viruses) include several clinically important viruses, such as dengue, Zika, yellow fever, West Nile, and chikungunya virus. Since there are no antiviral drugs or safe and effective FDA-approved vaccines…